NAPRT1 Protein (His tag)

N° du produit ABIN2745752

Détail du produit

Antigène: NAPRT1 (NAPRT) (Nicotinate phosphoribosyltransferase (NAPRT))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette NAPRT1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Réactivité croisée: Humain

Attributs du produit: Human NAPRTase is fused at the N-terminus to a His-tag.

Pureté: >98 % (SDS-PAGE)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

~0.27 U/mg protein. One unit is defined as the amount of enzyme that synthesizes 1μmol nicotinic acid mononucleotide (NaMN) per min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: In 50 mM HEPES/KOH pH 7.5 containing 300 mM potassium chloride and 10 mM DTT.

Agent conservateur: Dithiothreitol (DTT)

Précaution d'utilisation: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Short Term Storage: -20°C
Long Term Storage: -80°C
Stable for at least 6 months after receipt when stored at -80°C.

Date de péremption: 6 months

Détail du antigène

Antigène: NAPRT1 (NAPRT) (Nicotinate phosphoribosyltransferase (NAPRT))

Autre désignation: NAPRTase (NAPRT Produits)

Synonymes: PP3856 Protein, 9130210N20Rik Protein, zgc:77870 Protein, nicotinate phosphoribosyltransferase Protein, NAPRT Protein, Naprt Protein, naprt Protein

Sujet: Human nicotinate phosphoribosyltransferase (NAPRTase) is localized in the cytoplasm and is involved in biological processes such as NAD biosynthetic and metabolic processes, nicotinamide metabolic process, nicotinate nucleotide salvage, response to oxidative stress and water-soluble vitamin metabolic process. It functions by catalyzing the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN) and is essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells. It is a crucial factor in the NAD+ biosynthesis pathway. Catalytic activity: Beta-nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate.

Poids moléculaire: ~58.0kDa

UniProt: Q6XQN6