NMNAT1 Protein (AA 1-279) (His tag)

N° du produit ABIN2745771

Détail du produit

Antigène: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: AA 1-279

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette NMNAT1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Réactivité croisée: Humain

Attributs du produit: Human full-length NMNAT1 (aa 1-279) is fused at the N-terminus to a His-tag.

Pureté: >95 % (SDS-PAGE)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

>5U/mg protein. One unit is defined as the amount of enzyme that synthesizes 1μmol of NAD+ per min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: In 50 mM sodium phosphate, pH 8.0, containing 300 mM sodium chloride, 2 mM DTT and 10 % glycerol.

Agent conservateur: Dithiothreitol (DTT)

Précaution d'utilisation: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C.

Détail du antigène

Antigène: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Autre désignation: NMNAT1 (NMNAT1 Produits)

Synonymes: id:ibd5068 Protein, im:7144541 Protein, zgc:110243 Protein, LCA9 Protein, NMNAT Protein, PNAT1 Protein, 2610529L11Rik Protein, 5730441G13Rik Protein, D4Cole1e Protein, nmnat Protein, nicotinamide mononucleotide adenylyltransferase 1 Protein, nicotinamide nucleotide adenylyltransferase 1 Protein, CpipJ_CPIJ015320 Protein, PTRG_06486 Protein, nmnat1 Protein, NMNAT1 Protein, Nmnat1 Protein

Sujet: Nuclear NMNAT isoform. Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Interacts with PARP-1/ARTD1. Protects against axonal degeneration following mechanical or toxic insults. Widely expressed.

Poids moléculaire: ~33.3kDa (monomer)

UniProt: Q9HAN9