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PARP3 Protein (HA tag,His tag)

PARP3 Origine: Humain Hôte: Insect cells (Sf21) Recombinant >98 % (SDS-PAGE) SDS Active
N° du produit ABIN2745796
  • Antigène Voir toutes PARP3 Protéines
    PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Origine
    Humain
    Source
    • 1
    • 1
    • 1
    • 1
    • 1
    Insect cells (Sf21)
    Purification/Conjugué
    Cette PARP3 protéine est marqué à la HA tag,His tag.
    Application
    SDS-PAGE (SDS)
     Réactivité croisée
    Humain
    Attributs du produit
    Human full-length PARP-3 [ARTD3] is fused to a HA-tag and a His-tag.
    Pureté
    >98 % (SDS-PAGE)
    Top Product
    Discover our top product PARP3 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Commentaires

    >10U/mg protein (only monoADP-ribosyl transferase activity).

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    In 50 mM TRIS-HCl, pH 7.5, containing 100 mM sodium chloride and 50 mM imidazole, 0.2 % NP-40 and 10 % glycerol.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Short Term Storage: -20°C
    Long Term Storage: -80°C
    Stable for at least 6 months after receipt when stored at -80°C.
    Date de péremption
    6 months
  • Antigène
    PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))
    Autre désignation
    PARP-3 [ARTD3] (PARP3 Produits)
    Synonymes
    ADPRT-3 Protein, PARP-3 Protein, PM38 Protein, Adprtl3 Protein, fj17c06 Protein, wu:fj17c06 Protein, zgc:66157 Protein, PARP3 Protein, parp3 Protein, ADPRT3 Protein, ADPRTL2 Protein, ADPRTL3 Protein, ARTD3 Protein, IRT1 Protein, PADPRT-3 Protein, A930002C11Rik Protein, AW990611 Protein, Adprt3 Protein, pADPRT-3 Protein, seed maturation protein PM38 Protein, poly (ADP-ribose) polymerase family, member 3 Protein, poly(ADP-ribose) polymerase family member 3 Protein, poly(ADP-ribose) polymerase family member 3 L homeolog Protein, PARP3 Protein, parp3 Protein, parp3.L Protein, Parp3 Protein
    Sujet
    PARP-3 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
    UniProt
    Q9Y6F1
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