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POP1 Protein (AA 2-89) (GST tag)

POP1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant >95 % (SDS-PAGE) SDS
N° du produit ABIN2745804
  • Antigène Voir toutes POP1 Protéines
    POP1 (Processing of Precursor 1, Ribonuclease P/MRP Subunit (S. Cerevisiae) (POP1))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 2-89
    Origine
    Humain
    Source
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette POP1 protéine est marqué à la GST tag.
    Application
    SDS-PAGE (SDS)
     Réactivité croisée
    Humain
    Attributs du produit
    Human POP1 (aa 2-89) is fused at the N-terminus to a GST tag.
    Pureté
    >95 % (SDS-PAGE)
    Top Product
    Discover our top product POP1 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with 100 μL sterile water.
    Concentration
    Lot specific
    Buffer
    Lyophilized. Contains PBS.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Date de péremption
    6 months
  • Antigène
    POP1 (Processing of Precursor 1, Ribonuclease P/MRP Subunit (S. Cerevisiae) (POP1))
    Autre désignation
    POP1 (POP1 Produits)
    Synonymes
    4932434G09Rik Protein, POP1 homolog, ribonuclease P/MRP subunit Protein, processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae) Protein, POP1 Protein, Pop1 Protein
    Sujet
    The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor family (NLRs), including NLRP3/NALP3, are critical components of the inflammasome that link danger-signals to caspase-1 activation. Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS) and of chronic infantile neurologic cutaneous and articular syndrome (CINCA). Pyrin domain-containing protein 1 (POP1) interacts with the protein Asc (Pycard) and modulates the interaction of Asc to NLR proteins.
    Poids moléculaire
    ~38 kDa
    UniProt
    Q8WXC3
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