IL1RAP Protein (AA 21-359) (His tag)

N° du produit ABIN2749236

Détail du produit

Antigène: IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

Type de proteíne: Recombinant

Attributs du protein: AA 21-359

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IL1RAP protéine est marqué à la His tag.

Séquence: AA 21-359

Attributs du produit: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 40 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Pureté: >95 % as determined by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Conseil sur la manipulation: Please avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Détail du antigène

Antigène: IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

Autre désignation: IL-1 RAcP (IL1RAP Produits)

Synonymes: IL1RAP Protein, il-1racp Protein, il-racp Protein, il1r3 Protein, C3orf13 Protein, IL-1RAcP Protein, IL1R3 Protein, 6430709H04Rik Protein, AI255955 Protein, AV239853 Protein, IL-1RAcp Protein, Il1racpb Protein, interleukin 1 receptor accessory protein Protein, IL1RAP Protein, il1rap Protein, il-1racp Protein, Il1rap Protein

Sujet: Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. IL-1R3 / IL1RAP is coreceptor with IL1R1, associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.

Poids moléculaire: 40.2 kDa

UniProt: Q9NPH3

Pathways: Signalisation NF-kappaB, Growth Factor Binding