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LAG3 Protein (AA 24-442) (His tag)

LAG3 Origine: Rat Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
N° du produit ABIN2870839
  • Antigène Voir toutes LAG3 Protéines
    LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 24-442
    Origine
    • 19
    • 11
    • 6
    • 3
    • 1
    • 1
    • 1
    Rat
    Source
    • 20
    • 8
    • 4
    • 4
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette LAG3 protéine est marqué à la His tag.
    Séquence
    AA 24-442
    Attributs du produit
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 47.6 kDa. The protein migrates as 55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Pureté
    >90 % as determined by SDS-PAGE.
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product LAG3 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Conseil sur la manipulation
    Please avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
  • Antigène
    LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
    Autre désignation
    LAG-3 (LAG3 Produits)
    Synonymes
    CD223 Protein, LAG-3 Protein, Ly66 Protein, lymphocyte activating 3 Protein, lymphocyte-activation gene 3 Protein, LAG3 Protein, Lag3 Protein
    Sujet
    Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.
    Poids moléculaire
    47.6 kDa
    NCBI Accession
    NP_997678
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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