CEACAM1 Protein (AA 35-428) (His tag,AVI tag,Biotin)
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- Antigène Voir toutes CEACAM1 Protéines
- CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 35-428
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette CEACAM1 protéine est marqué à la His tag,AVI tag,Biotin.
- Séquence
- AA 35-428
- Specificité
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
- Attributs du produit
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High Quality Authentic Human CEACAM1 Protein
- The production of this recombinant, biotinylated CEACAM1 protein is carried out using a proprietary expression platform.
- As expression hosts, the human HEK293 cells have a variety of advantages compared to other cell types.
- Most importantly, the proteins retain their authentic post-translational processing, which often translates into high bioactivity and stability.
- The bioactivity of biotinylated proteins is determined both by the structure of the protein itself, and by the way how biotinylation is performed.
- For every single protein, multiple options of tags and biotinylation methods are tested and the products are evaluated in a variety of binding assays.
- Only those with the best performance are selected for production.
- Products are routinely tested using rigorous quality control measures to ensure consistent performance.
- Newly produced products are subjected to side-by-side comparison with our internal standard in a variety of assays.
- Only those within an acceptable margin of difference are allowed to be released.
- Pureté
- >95 % as determined by reduced SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product CEACAM1 Protéine
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- Commentaires
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Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Conseil sur la manipulation
- Please avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
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- Antigène
- CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))
- Autre désignation
- CEACAM1 (CEACAM1 Produits)
- Synonymes
- BGP Protein, BGP1 Protein, BGPI Protein, CD66e Protein, CEA Protein, zeh0068 Protein, hm:zeh0068 Protein, CEACAM8 Protein, CEACAM1 Protein, MGC142545 Protein, BGPR Protein, Bgp Protein, CD66a Protein, Ccam1 Protein, Bgp1 Protein, C-CAM Protein, Cc1 Protein, Cea-1 Protein, Cea-7 Protein, Cea1 Protein, Cea7 Protein, Hv-2 Protein, Hv2 Protein, MHVR Protein, MHVR1 Protein, Mhv-1 Protein, bb-1 Protein, mCEA1 Protein, mmCGM1 Protein, mmCGM1a Protein, mmCGM2 Protein, carcinoembryonic antigen related cell adhesion molecule 1 Protein, carcinoembryonic antigen related cell adhesion molecule 5 Protein, carcinoembryonic antigen-related cell adhesion molecule 1 Protein, carcinoembryonic antigen-related cell adhesion molecule 6 Protein, CEACAM1 Protein, CEACAM5 Protein, ceacam1 Protein, Ceacam1 Protein, LOC101103343 Protein
- Sujet
- Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is also known as Biliary glycoprotein 1 (BGP1), CD66a, which belongs to the immunoglobulin superfamily or CEA family. CEACAM1 /CD66a contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CEACAM1 /CD66a was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 / BGP-1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.
- Poids moléculaire
- 45.9 kDa
- NCBI Accession
- NP_001703
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