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CEACAM1 Protein (AA 35-428) (His tag,AVI tag,Biotin)

CEACAM1 Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE.
N° du produit ABIN3137678
  • Antigène Voir toutes CEACAM1 Protéines
    CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 35-428
    Origine
    • 19
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    Humain
    Source
    • 12
    • 11
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette CEACAM1 protéine est marqué à la His tag,AVI tag,Biotin.
    Séquence
    AA 35-428
    Specificité
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
    Attributs du produit
    High Quality Authentic Human CEACAM1 Protein
    • The production of this recombinant, biotinylated CEACAM1 protein is carried out using a proprietary expression platform.
    • As expression hosts, the human HEK293 cells have a variety of advantages compared to other cell types.
    • Most importantly, the proteins retain their authentic post-translational processing, which often translates into high bioactivity and stability.
    High Bioactivity & Detection Sensitivity
    • The bioactivity of biotinylated proteins is determined both by the structure of the protein itself, and by the way how biotinylation is performed.
    • For every single protein, multiple options of tags and biotinylation methods are tested and the products are evaluated in a variety of binding assays.
    • Only those with the best performance are selected for production.
    Low Batch-to-Batch Variation
    • Products are routinely tested using rigorous quality control measures to ensure consistent performance.
    • Newly produced products are subjected to side-by-side comparison with our internal standard in a variety of assays.
    • Only those within an acceptable margin of difference are allowed to be released.
    Pureté
    >95 % as determined by reduced SDS-PAGE.
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CEACAM1 Protéine
  • Commentaires

    Ready-to-use AvitagTM biotinylated protein:
    The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Conseil sur la manipulation
    Please avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
  • Antigène
    CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))
    Autre désignation
    CEACAM1 (CEACAM1 Produits)
    Synonymes
    BGP Protein, BGP1 Protein, BGPI Protein, CD66e Protein, CEA Protein, zeh0068 Protein, hm:zeh0068 Protein, CEACAM8 Protein, CEACAM1 Protein, MGC142545 Protein, BGPR Protein, Bgp Protein, CD66a Protein, Ccam1 Protein, Bgp1 Protein, C-CAM Protein, Cc1 Protein, Cea-1 Protein, Cea-7 Protein, Cea1 Protein, Cea7 Protein, Hv-2 Protein, Hv2 Protein, MHVR Protein, MHVR1 Protein, Mhv-1 Protein, bb-1 Protein, mCEA1 Protein, mmCGM1 Protein, mmCGM1a Protein, mmCGM2 Protein, carcinoembryonic antigen related cell adhesion molecule 1 Protein, carcinoembryonic antigen related cell adhesion molecule 5 Protein, carcinoembryonic antigen-related cell adhesion molecule 1 Protein, carcinoembryonic antigen-related cell adhesion molecule 6 Protein, CEACAM1 Protein, CEACAM5 Protein, ceacam1 Protein, Ceacam1 Protein, LOC101103343 Protein
    Sujet
    Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is also known as Biliary glycoprotein 1 (BGP1), CD66a, which belongs to the immunoglobulin superfamily or CEA family. CEACAM1 /CD66a contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CEACAM1 /CD66a was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 / BGP-1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.
    Poids moléculaire
    45.9 kDa
    NCBI Accession
    NP_001703
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