Alanyl (Membrane) Aminopeptidase (ANPEP) (Met603Ile-Mutant), (Metalloprotease Domain) (Active) protein (His tag)
Détails pour le produit réf. ABIN3216379- Nom de la protéine
-
trouver des synonymes de cet antigène
- APN
- CD13
- GP150
- LAP1
- P150
- PEPN
- Apn
- pepN
- SC8E4A.13
- AP-M
- AP-N
- Cd13
- Apm
- KZP
- Lap1
- rAPN
- APDE
- p150
- anpep
- fb64c05
- wu:fb64c05
- zgc:136771
- alanyl aminopeptidase, membrane
- aminopeptidase N
- aminopeptidase
- aminopeptidase n
- alanyl (membrane) aminopeptidase
- alanyl (membrane) aminopeptidase b
- alanyl aminopeptidase, membrane L homeolog
- ANPEP
- Apn2
- Apn1
- SCO2643
- pepN
- Shewana3_0897
- Alvin_1024
- Ndas_3413
- Saut_1544
- Fbal_1877
- ML5_3424
- Despr_1988
- Mesop_5365
- Anpep
- anpepb
- anpep.L
- Attributs du protein
-
Metalloprotease Domain, Met603Ile-Mutant
Alternatives - Origine
-
Humain
Alternatives - Source
-
Human Cells
Alternatives - Type de proteíne
- Recombinant
- Activité biologique
- Active
- Purification/Conjugué
-
Cette CD13 protéine est marqué à la His tag.
- Application
-
Functional Studies (Func), SDS-PAGE (SDS)
- Options
Indications d'application | Optimal working dilution should be determined by the investigator. |
Restrictions | For Research Use only |
Format | Lyophilized |
Buffer |
Lyophilized from sterile PBS, pH 7.3 Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. |
Conseil sur la manipulation | Avoid repeated freeze-thaw cycles. It is recommended that the protein be aliquoted for optimal storage. |
Stock | -20 °C,-80 °C |
Stockage commentaire |
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Date de péremption | 12 months |
Images (Fournisseur) |
Produit citée dans: |
Li, Hao, He, Meng, Li, Xue, Zhang, Li, Zhang, Zhang: "Recombinant IFN-?2a-NGR exhibits higher inhibitory function on tumor neovessels formation compared with IFN-?2a in vivo and in vitro." dans: Cytotechnology, 2014 (PubMed).
|
Background publications |
Petrovic, Bhagwat, Ratzan, Ostrowski, Shapiro: "CD13/APN transcription is induced by RAS/MAPK-mediated phosphorylation of Ets-2 in activated endothelial cells." dans: The Journal of biological chemistry, Vol. 278, Issue 49, pp. 49358-68, 2003
Bhagwat, Petrovic, Okamoto, Shapiro: "The angiogenic regulator CD13/APN is a transcriptional target of Ras signaling pathways in endothelial morphogenesis." dans: Blood, Vol. 101, Issue 5, pp. 1818-26, 2003 (PubMed). Petrovic, Bhagwat, Ratzan, Ostrowski, Shapiro: "CD13/APN transcription is induced by RAS/MAPK-mediated phosphorylation of Ets-2 in activated endothelial cells." dans: The Journal of biological chemistry, Vol. 278, Issue 49, pp. 49358-68, 2003 (PubMed). Pasqualini, Koivunen, Kain, Lahdenranta, Sakamoto, Stryhn, Ashmun, Shapiro, Arap, Ruoslahti: "Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis." dans: Cancer research, Vol. 60, Issue 3, pp. 722-7, 2000 (PubMed). Falk, Rötzschke, Stevanovi?, Jung, Rammensee: "Pool sequencing of natural HLA-DR, DQ, and DP ligands reveals detailed peptide motifs, constraints of processing, and general rules." dans: Immunogenetics, Vol. 39, Issue 4, pp. 230-42, 1994 (PubMed). Yeager, Ashmun, Williams, Cardellichio, Shapiro, Look, Holmes: "Human aminopeptidase N is a receptor for human coronavirus 229E." dans: Nature, Vol. 357, Issue 6377, pp. 420-2, 1992 (PubMed). |
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