Regenerating Islet-Derived 3 alpha (REG3A) (AA 1-175) protein (His tag)

Détails pour le produit réf. ABIN3216396
Nom de la protéine
  • HIP
  • HIP/PAP
  • INGAP
  • PAP
  • PAP-H
  • PAP1
  • PBCGF
  • REG-III
  • REG3
  • AV063448
  • Pap2
  • PapII
  • PTP
  • REG3G
  • regenerating family member 3 alpha
  • regenerating islet-derived 3 alpha
  • REG3A
  • Reg3a
Attributs du protein
AA 1-175
4
3
2
2
2
1
1
1
1
1
1
Origine
Humain
14
5
4
1
Source
Human Cells
7
4
3
3
3
2
Type de proteíne
Recombinant
Purification/Conjugué
Cette REG3A protéine est marqué à la His tag.
Application
SDS-PAGE (SDS)
Options
Attributs du produit The recombinant human REG3A consists of 160 amino acids after removal of the signal peptide and has a predicted molecular mass of 18 kDa as estimated in SDS-PAGE under reducing conditions.

Protein Structure: A DNA sequence encoding the human REG3A (Q06141-1) (Met 1-Asp 175) precursor was fused with a polyhistidine tag at the C-terminus.
Predicted N-Term: Glu 27
Pureté > 97 % as determined by SDS-PAGE
niveau d'endotoxine < 1.0 EU per μg of the protein as determined by the LAL method
Nom de la protéine
Sujet Synonyms: HIP,HIP/PAP,INGAP,PAP,PAP-H,PAP1,PBCGF,REG-III,REG3,REG3A,REG3V
Poids moléculaire 18 kDa
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Buffer Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
Conseil sur la manipulation Avoid repeated freeze-thaw cycles. It is recommended that the protein be aliquoted for optimal storage.
Stock -20 °C,-80 °C
Stockage commentaire Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Date de péremption 12 months
Images (Fournisseur)
 image for Regenerating Islet-Derived 3 alpha (REG3A) (AA 1-175) protein (His tag) (ABIN3216396) Regenerating Islet-Derived 3 alpha (REG3A) (AA 1-175) protein (His tag)
Produit citée dans: Wang, Zhou, Han, Liu, Wang, Wang, Yin, Li, Xiang: "SOCS3 methylation in synergy with Reg3A overexpression promotes cell growth in pancreatic cancer." dans: Journal of molecular medicine (Berlin, Germany), Vol. 92, Issue 12, pp. 1257-69, 2014 (PubMed).

Background publications Cavard, Terris, Grimber, Christa, Audard, Radenen-Bussiere, Simon, Renard, Buendia, Perret: "Overexpression of regenerating islet-derived 1 alpha and 3 alpha genes in human primary liver tumors with beta-catenin mutations." dans: Oncogene, Vol. 25, Issue 4, pp. 599-608, 2006 (PubMed).

Orelle, Keim, Masciotra, Dagorn, Iovanna: "Human pancreatitis-associated protein. Messenger RNA cloning and expression in pancreatic diseases." dans: The Journal of clinical investigation, Vol. 90, Issue 6, pp. 2284-91, 1993

Orelle, Keim, Masciotra, Dagorn, Iovanna: "Human pancreatitis-associated protein. Messenger RNA cloning and expression in pancreatic diseases." dans: The Journal of clinical investigation, Vol. 90, Issue 6, pp. 2284-91, 1993 (PubMed).

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