Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (AA 134-285) (Active) protein (Fc Tag)

Détails pour le produit réf. ABIN3216414
Nom de la protéine
  • RGD1561519
  • TNFSF13B
  • BAFF
  • BLYS
  • CD257
  • DTL
  • TALL-1
  • TALL1
  • THANK
  • TNFSF20
  • ZTNF4
  • BLyS
  • D8Ertd387e
  • zTNF4
  • TNF superfamily member 13b
  • tumor necrosis factor (ligand) superfamily, member 13b
  • Tnfsf13b
  • TNFSF13B
Attributs du protein
AA 134-285
17
9
6
4
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Origine
Cynomolgus
74
20
5
1
1
Source
Human Cells
45
19
6
5
5
3
2
1
Type de proteíne
Recombinant
Activité biologique
Active
Purification/Conjugué
Cette TNFSF13B protéine est marqué à la Fc Tag.
Application
Functional Studies (Func), SDS-PAGE (SDS)
Options
Attributs du produit The recombinant cynomolgus TNFSF13B is a disulfide-linked homodimer. The reduced monomer comprises 412 amino acids and has a calculated molecular mass of 45.5 KDa.The apparent molecular mass of the protein is approximately 47 KDa respectively in SDS-PAGE.

Protein Structure: A DNA sequence encoding the cynomolgus TNFSF13B (F7H548) (Ala134-Leu285) was expressed with the Fc region of human IgG1 at the C-terminus.
Predicted N-Term: Glu
Pureté > 95 % as determined by SDS-PAGE
niveau d'endotoxine < 1.0 EU per μg of the protein as determined by the LAL method
Biological Activity Comment Measured by its binding ability in a functional ELISA.
Immobilized Cynomolgus Fc-TNFSF13B at 10 μg/ml (100 μl/well) can bind biotinylated Cynomolgus TNFRSF17-Fc , the EC50 of biotinylated Cynomolgus TNFRSF17-Fc is 4.5-10.5 ng/ml.
Nom de la protéine
UniProt F7H548
Pathways Signalisation NF-kappaB, Production of Molecular Mediator of Immune Response
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Buffer Lyophilized from sterile PBS, PH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
Conseil sur la manipulation Avoid repeated freeze-thaw cycles. It is recommended that the protein be aliquoted for optimal storage.
Stock -20 °C,-80 °C
Stockage commentaire Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Date de péremption 12 months
Images (Fournisseur)
 image for Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (AA 134-285) (Active) protein (Fc Tag) (ABIN3216414) Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (AA 134-285) (Active) protein (Fc Tag)
Background publications Oren, Li, Volovik, Morris, Dharia, Das, Galperina, Gentz, Arnold: "Structural basis of BLyS receptor recognition." dans: Nature structural biology, Vol. 9, Issue 4, pp. 288-92, 2002 (PubMed).

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