Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 1-358) Protéine

Détails pour le produit réf. ABIN3216429
Nom de la protéine
  • ERK
  • ERK2
  • ERT1
  • MAPK2
  • P42MAPK
  • PRKM1
  • PRKM2
  • p38
  • p40
  • p41
  • p41mapk
  • 9030612K14Rik
  • AA407128
  • AU018647
  • C78273
  • Erk2
  • Prkm1
  • p42mapk
  • zERK2
  • MAPK1
  • Xp42
  • erk
  • erk2
  • ert1
  • mapk
  • mapk1b
  • mapk2
  • mpk1
  • prkm1
  • prkm2
  • mapk1
  • mapk1a
  • xp42
  • ATMPK1
  • F14N23.9
  • F14N23_9
  • MITOGEN-ACTIVATED PROTEIN KINASE
  • mitogen-activated protein kinase 1
  • mitogen-activated protein kinase 1
  • mitogen activated protein kinase 1
  • mitogen-activated protein kinase 1 L homeolog
  • mitogen-activated protein kinase 1 S homeolog
  • MAPK1
  • Mapk1
  • mapk1
  • mapk1.L
  • mapk1.S
  • PfMAP1
  • MPK1
  • PVX_084965
  • LOC9328617
  • Tsp_01601
Attributs du protein
AA 1-358
7
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Origine
Souris
23
5
5
2
2
1
1
Source
Baculovirus infected Insect Cells
10
7
4
3
2
2
2
Type de proteíne
Recombinant
Application
SDS-PAGE (SDS)
Options
Attributs du produit The recombinant mouse MAPK1 consists of 360 amino acids and predicts a molecular mass of 41.4 KDa. It migrates as an approximately 37 KDa band in SDS-PAGE under reducing conditions.

Protein Structure: A DNA sequence encoding the mouse MAPK1(P63085) (Met1-Ser358) was expressed and purified with two additional amino acids (Gly & Pro ) at the N-terminus.
Predicted N-Term: Gly
Pureté > 95 % as determined by SDS-PAGE
niveau d'endotoxine < 1.0 EU per μg of the protein as determined by the LAL method
Biological Activity Comment Kinase activity untested
Nom de la protéine
Sujet Synonyms: 9030612K14Rik,AA407128,AU018647,C78273,ERK,Erk2,MAPK2,p41mapk,p42mapk,Prkm1,PRKM2
UniProt P63085
Pathways Signalisation MAPK, Signalisation RTK, Apoptose, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagy, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Buffer Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % gly, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
Conseil sur la manipulation Avoid repeated freeze-thaw cycles. It is recommended that the protein be aliquoted for optimal storage.
Stock -20 °C,-80 °C
Stockage commentaire Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping: Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice.
Shipment made at ambient temperature may seriously affect the activity of the ordered products.
Date de péremption 12 months
Images (Fournisseur)
 image for Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 1-358) protein (ABIN3216429) Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 1-358) protein
Background publications Slack, Seternes, Gabrielsen, Keyse: "Distinct binding determinants for ERK2/p38alpha and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1." dans: The Journal of biological chemistry, Vol. 276, Issue 19, pp. 16491-500, 2001 (PubMed).

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