C-Src tyrosine Kinase (CSK) (AA 1-450) Protéine

Détails pour le produit réf. ABIN3216432
Nom de la protéine
  • AW212630
  • C-terminal Src kinase
  • c-src tyrosine kinase
  • CSK, non-receptor tyrosine kinase
  • CSK
  • Csk
Attributs du protein
AA 1-450
7
4
1
1
1
1
1
Origine
Souris
17
2
1
1
1
Source
Baculovirus infected Insect Cells
6
4
3
3
2
2
1
1
Type de proteíne
Recombinant
Application
SDS-PAGE (SDS)
Options
Attributs du produit The recombinant mouse CSK consists of 452 amino acids and predicts a molecular mass of 50.9 KDa. It migrates as an approximately 46 KDa band in SDS-PAGE under reducing conditions.

Protein Structure: A DNA sequence encoding the mouse CSK (P41241 ) (Met 1-Leu 450) was expressed and purified with two additional amino acids (Gly & Pro ) at the N-terminus.
Predicted N-Term: Gly
Pureté > 90 % as determined by SDS-PAGE
niveau d'endotoxine < 1.0 EU per μg of the protein as determined by the LAL method
Biological Activity Comment Kinase activity untested
Nom de la protéine
Sujet Synonyms: AW212630,p50CSK
UniProt P41241
Pathways TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Buffer Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
Conseil sur la manipulation Avoid repeated freeze-thaw cycles. It is recommended that the protein be aliquoted for optimal storage.
Stock -20 °C,-80 °C
Stockage commentaire Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping: Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice.
Shipment made at ambient temperature may seriously affect the activity of the ordered products.
Date de péremption 12 months
Images (Fournisseur)
 image for C-Src tyrosine Kinase (CSK) (AA 1-450) protein (ABIN3216432) C-Src tyrosine Kinase (CSK) (AA 1-450) protein
Background publications Bräuninger, Holtrich, Strebhardt, Rübsamen-Waigmann: "Isolation and characterization of a human gene that encodes a new subclass of protein tyrosine kinases." dans: Gene, Vol. 110, Issue 2, pp. 205-11, 1992 (PubMed).

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