BCMA (TNFRSF17)
(Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
Type de proteíne
Recombinant
Activité biologique
Active
Attributs du protein
AA 1-54
Origine
Humain
Source
HEK-293 Cells
Purification/Conjugué
Cette BCMA protéine est marqué à la His tag.
Application
Functional Studies (Func)
Séquence
AA 1-54
Attributs du produit
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 7.5 kDa. the protein migrates as 7-15 kDa under reducing (R) condition, and 15-18 kDa under non-reducing (NR) condition (SDS-PAGE).
TNFRSF17
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
ELISA
Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.