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IGFBP2 Protéine

IGFBP2 Origine: Humain Hôte: Hi-5 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining STD, AbP, Func, PI Active
N° du produit ABIN5505672
  • Antigène Voir toutes IGFBP2 Protéines
    IGFBP2 (Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Origine
    • 9
    • 7
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain
    Source
    • 13
    • 8
    • 8
    • 2
    • 1
    • 1
    Hi-5 Cells
    Application
    Standard (STD), Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI)
    Specificité
    Optimal preservation of protein structure, post-translational modifications and functions.
    Attributs du produit
    • Recombinant human IGFBP2 protein expressed in Hi-5 insect cells.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Pureté
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    niveau d'endotoxine
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    Determined by its ability to inhibit IGF-I induced proliferation of FDC-P1 cells.
    Top Product
    Discover our top product IGFBP2 Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Restrictions
    For Research Use only
  • Buffer
    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
    Conseil sur la manipulation
    Resuspend the protein in the desired concentration in proper buffer
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    IGFBP2 (Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2))
    Autre désignation
    IGFBP2 (IGFBP2 Produits)
    Synonymes
    IBP2 Protein, IGF-BP53 Protein, AI255832 Protein, IBP-2 Protein, Igfbp-2 Protein, mIGFBP-2 Protein, IGFBP-2 Protein, ILGFBPA Protein, pIGFBP-2 Protein, igfbp2 Protein, MGC65741 Protein, MGC76823 Protein, MGC174445 Protein, IGFBP2 Protein, ibp2 Protein, igf-bp53 Protein, igfbp2a Protein, si:ch211-2k18.3 Protein, insulin like growth factor binding protein 2 Protein, insulin-like growth factor binding protein 2 Protein, insulin-like growth factor binding protein 2a Protein, insulin-like growth factor binding protein 2b Protein, IGFBP2 Protein, Igfbp2 Protein, igfbp2a Protein, igfbp2 Protein, igfbp2b Protein
    Sujet
    The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene.
    Poids moléculaire
    31.5 kDa
    NCBI Accession
    NP_000588
    Pathways
    Myometrial Relaxation and Contraction, Growth Factor Binding, Activated T Cell Proliferation
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