Mre11 Protein (His tag)

N° du produit ABIN5505726

Détail du produit

Antigène: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Mre11 protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Purified recombinant protein of Human MRE11 meiotic recombination 11 homolog A (S. cerevisiae) (MRE11A), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50 μg (full length, N-term HIS tag, transcript variant 2) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Purification: Purified

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Autre désignation: MRE11 meiotic recombination 11 homolog A (MRE11A Produits)

Synonymes: wu:faa63d12 Protein, zgc:64018 Protein, Mre11 Protein, Mre11b Protein, ATLD Protein, HNGS1 Protein, MRE11 Protein, MRE11B Protein, MRE11 homolog A, double strand break repair nuclease Protein, MRE11 homolog, double strand break repair nuclease Protein, MRE11A homolog A, double strand break repair nuclease Protein, mre11a Protein, MRE11 Protein, Mre11a Protein

Sujet: This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3&apos to 5&apos exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3&apos to 5&apos exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Poids moléculaire: 77.5 kDa

NCBI Accession: NP_005581

Pathways: Réparation de l'ADN