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NMNAT2 Protein (AA 2-307) (His tag)

NMNAT2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant >90 % (SDS-PAGE) SDS
N° du produit ABIN5564378
  • Antigène Voir toutes NMNAT2 Protéines
    NMNAT2 (Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 2-307
    Origine
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette NMNAT2 protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
     Réactivité croisée
    Humain
    Attributs du produit
    Human NMNA2 (aa 2-307) is fused at the N-terminus to a His-tag.
    Pureté
    >90 % (SDS-PAGE)
    Top Product
    Discover our top product NMNAT2 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Solid
    Concentration
    Lot specific
    Buffer
    Lyophilized in 55 mM TRIS-Cl, pH 8.2, containing 150 mM NaCl plus 0.025 % CHAPS.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Date de péremption
    6 months
  • Antigène
    NMNAT2 (Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2))
    Autre désignation
    NMNAT2 (NMNAT2 Produits)
    Synonymes
    zgc:73048 Protein, wu:fj59g01 Protein, NMNAT2 Protein, C1orf15 Protein, PNAT2 Protein, AI843915 Protein, D030041I09Rik Protein, PNAT1 Protein, nicotinamide nucleotide adenylyltransferase 2 Protein, nmnat2 Protein, NMNAT2 Protein, Nmnat2 Protein
    Sujet
    Nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form nicotinic acid mononucleotide (NaMN) as a substrate but with lower efficiency. NMNAT2 also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. It is highly expressed in brain, in particular in cerebrum, cerebellum, occipital lobe, frontal lobe, temporal lobe and putamen. NMNAT2 is also found in the heart, skeletal muscle, pancreas and islets of Langerhans. NMNAT2 is essential for axon growth and survival. Its loss from injured axons may activate Wallerian degeneration (axon degeneration induced by nerve injury), whereas NMNAT overexpression rescues axons from degeneration.
    Poids moléculaire
    ~35kDa (SDS-PAGE)
    UniProt
    Q9BZQ4
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