NMNAT2 Protein (AA 2-307) (His tag)
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- Antigène Voir toutes NMNAT2 Protéines
- NMNAT2 (Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 2-307
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette NMNAT2 protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Réactivité croisée
- Humain
- Attributs du produit
- Human NMNA2 (aa 2-307) is fused at the N-terminus to a His-tag.
- Pureté
- >90 % (SDS-PAGE)
- Top Product
- Discover our top product NMNAT2 Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Solid
- Concentration
- Lot specific
- Buffer
- Lyophilized in 55 mM TRIS-Cl, pH 8.2, containing 150 mM NaCl plus 0.025 % CHAPS.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Date de péremption
- 6 months
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- Antigène
- NMNAT2 (Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2))
- Autre désignation
- NMNAT2 (NMNAT2 Produits)
- Synonymes
- zgc:73048 Protein, wu:fj59g01 Protein, NMNAT2 Protein, C1orf15 Protein, PNAT2 Protein, AI843915 Protein, D030041I09Rik Protein, PNAT1 Protein, nicotinamide nucleotide adenylyltransferase 2 Protein, nmnat2 Protein, NMNAT2 Protein, Nmnat2 Protein
- Sujet
- Nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form nicotinic acid mononucleotide (NaMN) as a substrate but with lower efficiency. NMNAT2 also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. It is highly expressed in brain, in particular in cerebrum, cerebellum, occipital lobe, frontal lobe, temporal lobe and putamen. NMNAT2 is also found in the heart, skeletal muscle, pancreas and islets of Langerhans. NMNAT2 is essential for axon growth and survival. Its loss from injured axons may activate Wallerian degeneration (axon degeneration induced by nerve injury), whereas NMNAT overexpression rescues axons from degeneration.
- Poids moléculaire
- ~35kDa (SDS-PAGE)
- UniProt
- Q9BZQ4
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