tau Protein (AA 2-459) (His-SUMO Tag)

N° du produit ABIN5709911

Détail du produit

Antigène: tau (tau Protein)

Type de proteíne: Recombinant

Attributs du protein: AA 2-459

Origine: Macaque rhésus

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette tau protéine est marqué à la His-SUMO Tag.

Application: SDS-PAGE (SDS)

Séquence: AEPRQEFDVM EDHAGTYGLG DRKDQEGYTM LQDQEGDTDA GLKESPLQTP AEDGSEELGS ETSDAKSTPT AEDVTAPLVD ERAPGEQAAA QPHMEIPEGT TAEEAGIGDT PSLEDEAAGH VTQARMVSKS KDGTGSDDKK AKGADGKTKI ATPRGAAPPG QKGQANATRI PAKTPPAPKT PPSSATKQVQ RKPPPAEPTS ERGEPPKSGD RSGYSSPGSP GTPGSRSRTP SLPTPPAREP KKVAVVRTPP KSPSSAKSRL QTAPVPMPDL KNVKSKIGST ENLKHQPGGG KVQIINKKLD LSNVQSKCGS KDNIKHVPGG GSVQIVYKPV DLSKVTSKCG SLGNIHHKPG GGQVEVKSEK LDFKDRVQSK IGSLDNITHV PGGGNKKIET HKLTFRENAK AKTDHGAEIV YKSPVVSGDT SPRHLSNVSS TGSIDMVDSP QLATLADEVS ASLAKQGL

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: tau (tau Protein)

Autre désignation: tau (tau Produits)

Synonymes: DDPAC Protein, FTDP-17 Protein, MAPTL Protein, MSTD Protein, MTBT1 Protein, MTBT2 Protein, PPND Protein, TAU Protein, tau Protein, PHF-tau Protein, microtubule associated protein tau Protein, MAPT Protein

Sujet: Promotes microtubule assbly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma mbrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Poids moléculaire: 63.8 kDa

UniProt: P57786