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NDST1 Protein (AA 40-556, Isoform 2) (His-SUMO Tag)

NDST1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5709995
  • Antigène Voir toutes NDST1 Protéines
    NDST1 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 40-556, Isoform 2
    Origine
    • 5
    • 2
    Humain
    Source
    • 4
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette NDST1 protéine est marqué à la His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    GWKRGLEPSA DAPEPDCGDP PPVAPSRLLP LKPVQAATPS RTDPLVLVFV ESLYSQLGQE VVAILESSRF KYRTEIAPGK GDMPTLTDKG RGRFALIIYE NILKYVNLDA WNRELLDKYC VAYGVGIIGF FKANENSLLS AQLKGFPLFL HSNLGLKDCS INPKSPLLYV TRPSEVEKGV LPGEDWTVFQ SNHSTYEPVL LAKTRSSESI PHLGADAGLH AALHATVVQD LGLHDGIQRV LFGNNLNFWL HKLVFVDAVA FLTGKRLSLP LDRYILVDID DIFVGKEGTR MKVEDVKALF DTQNELRAHI PNFTFNLGYS GKFFQTGTNA EDAGDDLLLS YVKEFWWFPH MWSHMQPHLF HNQSVLAEQM ALNKKFAVEH GIPTDMGYAV APHHSGVYPV HVQLYEAWKQ VWSIRVTSTE EYPHLKPARY RRGFIHNGIM VLPRQTCGLF THTIFYNEYP GGSSELDKII NGGELFLTVL LNPVSAPQPM AAGEKGLLHS LSAADTGFLE PGKGGEA
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product NDST1 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    NDST1 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1))
    Autre désignation
    NDST1 (NDST1 Produits)
    Synonymes
    HSST Protein, NST1 Protein, 1200015G06Rik Protein, Hsst Protein, NDST-1 Protein, fj47c03 Protein, ndst1 Protein, wu:fj47c03 Protein, NDST1 Protein, N-deacetylase and N-sulfotransferase 1 Protein, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 Protein, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b Protein, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 S homeolog Protein, NDST1 Protein, Ndst1 Protein, ndst1b Protein, ndst1 Protein, ndst1.S Protein
    Sujet
    Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response.
    Poids moléculaire
    73.5 kDa
    UniProt
    P52848
    Pathways
    Regulation of Systemic Arterial Blood Pressure by Hormones, Glycosaminoglycan Metabolic Process
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