ORC4 Protein (AA 1-436, full length) (His-SUMO Tag)

N° du produit ABIN5710049

Détail du produit

Antigène: ORC4 (Origin Recognition Complex, Subunit 4 (ORC4))

Type de proteíne: Recombinant

Attributs du protein: full length, AA 1-436

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette ORC4 protéine est marqué à la His-SUMO Tag.

Application: SDS-PAGE (SDS)

Séquence: MSSRKSKSNS LIHTECLSQV QRILRERFCR QSPHSNLFGV QVQYKHLSEL LKRTALHGES NSVLIIGPRG SGKTMLINHA LKELMEIEEV SENVLQVHLN GLLQINDKIA LKEITRQLNL ENVVGDKVFG SFAENLSFLL EALKKGDRTS SCPVIFILDE FDLFAHHKNQ TLLYNLFDIS QSAQTPIAVI GLTCRLDILE LLEKRVKSRF SHRQIHLMNS FGFPQYVKIF KEQLSLPAEF PDKVFAEKWN ENVQYLSEDR SVQEVLQKHF NISKNLRSLH MLLMLALNRV TASHPFMTAV DLMEASQLCS MDSKANIVHG LSVLEICLII AMKHLNDIYE EEPFNFQMVY NEFQKFVQRK AHSVYNFEKP VVMKAFEHLQ QLELIKPMER TSGNSQREYQ LMKLLLDNTQ IMNALQKYPN CPTDVRQWAT SSLSWL

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: ORC4 (Origin Recognition Complex, Subunit 4 (ORC4))

Autre désignation: ORC4 (ORC4 Produits)

Synonymes: ORC4L Protein, ORC4P Protein, Orc4P Protein, Orc4l Protein, mMmORC4 Protein, CG2917 Protein, DmORC4 Protein, Dmel\\CG2917 Protein, ORC Protein, ORC4 Protein, dmOrc4 Protein, orc4 Protein, rDmORC Protein, orc4l Protein, fc50c03 Protein, wu:fc50c03 Protein, zgc:85772 Protein, ATORC4 Protein, F23H14.9 Protein, F23H14_9 Protein, ORIGIN RECOGNITION COMPLEX SUBUNIT 4 Protein, origin recognition complex subunit 4 Protein, origin recognition complex subunit 4 Protein, origin recognition complex, subunit 4 Protein, Origin recognition complex subunit 4 Protein, origin recognition complex subunit 4 L homeolog Protein, origin recognition complex subunit Orc4 Protein, ORC4 Protein, Orc4 Protein, orc4.L Protein, orc4 Protein, CNM01830 Protein

Sujet: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.

Poids moléculaire: 66.3 kDa

UniProt: O43929

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA