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PPM1B Protein (AA 2-193) (His-SUMO Tag)

PPM1B Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5710135
  • Antigène Voir toutes PPM1B Protéines
    PPM1B (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 2-193
    Origine
    • 5
    • 1
    • 1
    • 1
    Humain
    Source
    • 3
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette PPM1B protéine est marqué à la His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    MSIVLVCFSN APKVSDEAVK KDSELDKHLE SRVEEIMEKS GEEGMPDLAH VMRILSAENI PNLPPGGGLA GKRNVIEAVY SRLNPHRESD GASDEAEESG SQGKLVEALR QMRINHRGNY RQLLEEMLTS YRLAKVEGEE SPAEPAATAT SSNSDAGNPV TMQESHTESE SGLAELDSSN EDAGTKMSGE KI
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product PPM1B Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    PPM1B (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B))
    Autre désignation
    PPM1B (PPM1B Produits)
    Synonymes
    PP2C-beta-X Protein, PP2CB Protein, PP2CBETA Protein, PPC2BETAX Protein, Pp2c2 Protein, fc18g04 Protein, ppm1a Protein, wu:fc18g04 Protein, zgc:92329 Protein, pp2c-beta-x Protein, pp2cb Protein, pp2cbeta Protein, ppc2betax Protein, zgc:92031 Protein, protein phosphatase, Mg2+/Mn2+ dependent 1B Protein, protein phosphatase 1B, magnesium dependent, beta isoform Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1B Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1Bb Protein, protein phosphatase, Mg2+/Mn2+ dependent 1B L homeolog Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1Ba Protein, PPM1B Protein, Ppm1b Protein, ppm1bb Protein, ppm1b.L Protein, ppm1ba Protein
    Sujet
    Enzyme with a broad specificity. Dephosphorylates CDK2 and CDK6 in vitro. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172'. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
    Poids moléculaire
    36.74 kDa
    UniProt
    O75688
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