PTGDS Protein (AA 23-190) (His-SUMO Tag)

N° du produit ABIN5710175

Détail du produit

Antigène: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Type de proteíne: Recombinant

Attributs du protein: AA 23-190

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PTGDS protéine est marqué à la His-SUMO Tag.

Application: SDS-PAGE (SDS)

Séquence: APEAQVSVQP NFQQDKFLGR WFSAGLASNS SWLREKKAAL SMCKSVVAPA TDGGLNLTST FLRKNQCETR TMLLQPAGSL GSYSYRSPHW GSTYSVSVVE TDYDQYALLY SQGSKGPGED FRMATLYSRT QTPRAELKEK FTAFCKAQGF TEDTIVFLPQ TDKCMTEQ

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Autre désignation: PTGDS (PTGDS Produits)

Synonymes: 6PGD Protein, GSTS Protein, GSTS1-1 Protein, PGD2 Protein, PGDS Protein, L-PGDS Protein, LPGDS Protein, PDS Protein, PGDS2 Protein, H-PGDS Protein, Ptgds2 Protein, 21kDa Protein, Ptgs3 Protein, PH2DISO Protein, phosphogluconate dehydrogenase Protein, hematopoietic prostaglandin D synthase Protein, prostaglandin D2 synthase Protein, prostaglandin D2 synthase (brain) Protein, prostaglandin D synthase Protein, prostaglandin D2 synthase 21kDa (brain) Protein, PGD Protein, HPGDS Protein, PTGDS Protein, Hpgds Protein, Ptgds Protein, LOC100009453 Protein

Sujet: Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NR sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous syst and male reproductive syst.

Poids moléculaire: 34.69 kDa

UniProt: P41222