PTPRB Protein (AA 1643-1997) (His-SUMO Tag)
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- Antigène Voir toutes PTPRB Protéines
- PTPRB (Protein tyrosine Phosphatase, Receptor Type, B (PTPRB))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1643-1997
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette PTPRB protéine est marqué à la His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- RQKVSHGRER PSARLSIRRD RPLSVHLNLG QKGNRKTSCP IKINQFEGHF MKLQADSNYL LSKEYEELKD VGRNQSCDIA LLPENRGKNR YNNILPYDAT RVKLSNVDDD PCSDYINASY IPGNNFRREY IVTQGPLPGT KDDFWKMVWE QNVHNIVMVT QCVEKGRVKC DHYWPADQDS LYYGDLILQM LSESVLPEWT IREFKICGEE QLDAHRLIRH FHYTVWPDHG VPETTQSLIQ FVRTVRDYIN RSPGAGPTVV HCSAGVGRTG TFIALDRILQ QLDSKDSVDI YGAVHDLRLH RVHMVQTECQ YVYLHQCVRD VLRARKLRSE QENPLFPIYE NVNPEYHRDP VYSRH
- Purification
- SDS-PAGE
- Pureté
- > 90 %
- Top Product
- Discover our top product PTPRB Protéine
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Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) (AA 1643-1997) protein (His tag)
Crystallography grade PTPRB Origine: Humain Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) (AA 1644-1997) protein (His tag)Crystallography grade PTPRB Origine: Souris Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) (AA 23-1621) protein (His tag)Crystallography grade PTPRB Origine: Humain Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) (AA 23-1622) protein (His tag)Crystallography grade PTPRB Origine: Souris Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) (AA 1643-1997) protein (His tag)PTPRB Origine: Humain Hôte: Levure Recombinant > 90 % SDS
Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PTPRB Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Antigène
- PTPRB (Protein tyrosine Phosphatase, Receptor Type, B (PTPRB))
- Autre désignation
- PTPRB (PTPRB Produits)
- Synonymes
- PTPRB Protein, HPTP-BETA Protein, HPTPB Protein, PTPB Protein, R-PTP-BETA Protein, VEPTP Protein, 3230402H02Rik Protein, C130094E24 Protein, Ptpz Protein, Rptpb Protein, VE-PTP Protein, Veptp Protein, protein tyrosine phosphatase, receptor type B Protein, receptor-type tyrosine-protein phosphatase beta Protein, protein tyrosine phosphatase, receptor type, B Protein, PTPRB Protein, LOC100380677 Protein, Ptprb Protein
- Sujet
- Plays an important role in blood vessel rodeling and angiogenesis. Not necessary for the initial formation of blood vessels, but is essential for their maintenance and rodeling. Can induce dephosphorylation of TEK/TIE2, CDH5/VE-cadherin and KDR/VEGFR-2. Regulates angiopoietin-TIE2 signaling in endothelial cells. Acts as a negative regulator of TIE2, and controls TIE2 driven endothelial cell proliferation, which in turn affects blood vessel rodeling during bryonic development and determines blood vessel size during perinatal growth. Essential for the maintenance of endothelial cell contact integrity and for the adhesive function of VE-cadherin in endothelial cells and this requires the presence of plakoglobin .
- Poids moléculaire
- 57.36 kDa
- UniProt
- P23467
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