SRSF1 Protein (AA 2-248) (His-SUMO Tag)
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- Antigène Voir toutes SRSF1 Protéines
- SRSF1 (serine/arginine-Rich Splicing Factor 1 (SRSF1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 2-248
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette SRSF1 protéine est marqué à la His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- SGGGVIRGPA GNNDCRIYVG NLPPDIRTKD IEDVFYKYGA IRDIDLKNRR GGPPFAFVEF EDPRDAEDAV YGRDGYDYDG YRLRVEFPRS GRGTGRGGGG GGGGGAPRGR YGPPSRRSEN RVVVSGLPPS GSWQDLKDHM REAGDVCYAD VYRDGTGVVE FVRKEDMTYA VRKLDNTKFR SHEGETAYIR VKVDGPRSPS YGRSRSRSRS RSRSRSRSNS RSRSYSPRRS RGSPRYSPRH SRSRSRT
- Purification
- SDS-PAGE
- Pureté
- > 90 %
- Top Product
- Discover our top product SRSF1 Protéine
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serine/arginine-Rich Splicing Factor 1 (SRSF1) (AA 1-248) protein (GST tag)
SRSF1 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
serine/arginine-Rich Splicing Factor 1 (SRSF1) (AA 2-248) protein (His tag)Crystallography grade SRSF1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
serine/arginine-Rich Splicing Factor 1 (SRSF1) (AA 2-248) protein (His tag)Crystallography grade SRSF1 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
serine/arginine-Rich Splicing Factor 1 (SRSF1) (AA 1-248) protein (His tag)SRSF1 Origine: Humain Hôte: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE SDS
serine/arginine-Rich Splicing Factor 1 (SRSF1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)SRSF1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Antigène
- SRSF1 (serine/arginine-Rich Splicing Factor 1 (SRSF1))
- Autre désignation
- SRSF1 (SRSF1 Produits)
- Sujet
- Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site-containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octamer constitute a powerful splicing enhancer in vitro, the ASF/SF2 splicing enhancer (ASE) which can specifically activate ASE-dependent splicing. Isoform ASF-2 and isoform ASF-3 act as splicing repressors. May function as export adapter involved in mRNA nuclear export through the TAP/NXF1 pathway.
- Poids moléculaire
- 43.6 kDa
- UniProt
- Q07955
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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