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SOX2 Protein (AA 1-317, full length) (His-SUMO Tag)

SOX2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5710406
  • Antigène Voir toutes SOX2 Protéines
    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
    Type de proteíne
    Recombinant
    Attributs du protein
    full length, AA 1-317
    Origine
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 9
    • 4
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette SOX2 protéine est marqué à la His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDR VKRPMNAFMV WSRGQRRKMA QENPKMHNSE ISKRLGAEWK LLSETEKRPF IDEAKRLRAL HMKEHPDYKY RPRRKTKTLM KKDKYTLPGG LLAPGGNSMA SGVGVGAGLG AGVNQRMDSY AHMNGWSNGS YSMMQDQLGY PQHPGLNAHG AAQMQPMHRY DVSALQYNSM TSSQTYMNGS PTYSMSYSQQ GTPGMALGSM GSVVKSEASS SPPVVTSSSH SRAPCQAGDL RDMISMYLPG AEVPEPAAPS RLHMSQHYQS GPVPGTAING TLPLSHM
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product SOX2 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
    Autre désignation
    SOX2 (SOX2 Produits)
    Synonymes
    ANOP3 Protein, MCOPS3 Protein, RGD1565646 Protein, Sox-2 Protein, lcc Protein, ysb Protein, cb236 Protein, wu:fb83g04 Protein, wu:fc14d07 Protein, zgc:65860 Protein, zgc:77389 Protein, SRY-box2 Protein, Xsox-2 Protein, anop3 Protein, mcops3 Protein, sox-2 Protein, SRY-box 2 Protein, SRY box 2 Protein, SRY (sex determining region Y)-box 2 Protein, SRY-box 2 S homeolog Protein, SOX2 Protein, Sox2 Protein, sox2 Protein, sox2.S Protein
    Sujet
    Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in bryonic development such as YES1, FGF4, UTF1 and ZFP206 . Critical for early bryogenesis and for bryonic st cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural st cell self-renewal . Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation .
    Poids moléculaire
    50.3 kDa
    UniProt
    P48431
    Pathways
    Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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