RRM1 Protein (AA 1-761, full length) (His-SUMO Tag)

N° du produit ABIN5710974

Détail du produit

Antigène: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Type de proteíne: Recombinant

Attributs du protein: full length, AA 1-761

Origine: E. coli

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette RRM1 protéine est marqué à la His-SUMO Tag.

Application: SDS-PAGE (SDS)

Séquence: MNQNLLVTKR DGSTERINLD KIHRVLDWAA EGLHNVSISQ VELRSHIQFY DGIKTSDIHE TIIKAAADLI SRDAPDYQYL AARLAIFHLR KKAYGQFEPP ALYDHVVKMV EMGKYDNHLL EDYTEEEFKQ MDTFIDHDRD MTFSYAAVKQ LEGKYLVQNR VTGEIYESAQ FLYILVAACL FSNYPRETRL QYVKRFYDAV STFKISLPTP IMSGVRTPTR QFSSCVLIEC GDSLDSINAT SSAIVKYVSQ RAGIGINAGR IRALGSPIRG GEAFHTGCIP FYKHFQTAVK SCSQGGVRGG AATLFYPMWH LEVESLLVLK NNRGVEGNRV RHMDYGVQIN KLMYTRLLKG EDITLFSPSD VPGLYDAFFA DQEEFERLYT KYEKDDSIRK QRVKAVELFS LMMQERASTG RIYIQNVDHC NTHSPFDPAI APVRQSNLCL EIALPTKPLN DVNDENGEIA LCTLSAFNLG AINNLDELEE LAILAVRALD ALLDYQDYPI PAAKRGAMGR RTLGIGVINF AYYLAKHGKR YSDGSANNLT HKTFEAIQYY LLKASNELAK EQGACPWFNE TTYAKGILPI DTYKKDLDTI ANEPLHYDWE ALRESIKTHG LRNSTLSALM PSETSSQISN ATNGIEPPRG YVSIKASKDG ILRQVVPDYE HLHDAYELLW EMPGNDGYLQ LVGIMQKFID QSISANTNYD PSRFPSGKVP MQQLLKDLLT AYKFGVKTLY YQNTRDGAED AQDDLVPSIQ DDGCESGACK I

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Autre désignation: RIR1 (RRM1 Produits)

Synonymes: CG5371 Protein, DmRNR1 Protein, Dmel\\CG5371 Protein, RNR1 Protein, RnrM1 Protein, RntL Protein, l(2)k06709 Protein, XRRM1 Protein, R1 Protein, RIR1 Protein, RR1 Protein, CHUNP6866 Protein, cb396 Protein, cb838 Protein, r1 Protein, sb:cb548 Protein, wu:fb39b07 Protein, wu:fi14b02 Protein, wu:fk95f07 Protein, ribonucleotide reductase catalytic subunit M1 Protein, Ribonucleoside diphosphate reductase large subunit Protein, ribonucleoside-diphosphate reductase large subunit Protein, ribonucleotide reductase M1 L homeolog Protein, ribonucleotide reductase M1 Protein, ribonucleotide reductase M1 polypeptide Protein, RRM1 Protein, RnrL Protein, LOC100472317 Protein, rrm1 Protein, rrm1.L Protein, Rrm1 Protein

Sujet: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. It also provides redox-active cysteines.

Poids moléculaire: 101.72 kDa

UniProt: P00452

Pathways: Positive Regulation of Endopeptidase Activity