TGS1 Protein (AA 713-853, partial) (His-SUMO Tag)
-
- Antigène Voir toutes TGS1 Protéines
- TGS1 (Trimethylguanosine Synthase 1 (TGS1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 713-853, partial
-
Origine
- Humain
-
Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette TGS1 protéine est marqué à la His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- MRVIAIDIDP VKIALARNNA EVYGIADKIE FICGDFLLLA SFLKADVVFL SPPWGGPDYA TAETFDIRTM MSPDGFEIFR LSKKITNNIV YFLPRNADID QVASLAGPGG QVEIEQNFLN NKLKTITAYF GDLIRRPASE T
- Purification
- SDS-PAGE
- Pureté
- > 90 %
- Top Product
- Discover our top product TGS1 Protéine
-
Trimethylguanosine Synthase 1 (TGS1) (AA 1-141) protein (GST tag)
TGS1 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AP, AA
Trimethylguanosine Synthase 1 (TGS1) (AA 1-853) protein (GST tag)TGS1 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AP, AA
Trimethylguanosine Synthase 1 (TGS1) (AA 1-853) protein (Strep Tag)Crystallography grade TGS1 Origine: Souris Hôte: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Trimethylguanosine Synthase 1 (TGS1) (AA 1-853) protein (Strep Tag)Crystallography grade TGS1 Origine: Humain Hôte: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
-
- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- Antigène
- TGS1 (Trimethylguanosine Synthase 1 (TGS1))
- Autre désignation
- TGS1 (TGS1 Produits)
- Synonymes
- NCOA6IP Protein, PIMT Protein, PIPMT Protein, D4Ertd800e Protein, Ncoa6ip Protein, Pimt Protein, trimethylguanosine synthase 1 Protein, trimethylguanosine synthase 1 L homeolog Protein, TGS1 Protein, Tgs1 Protein, tgs1.L Protein
- Sujet
- Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m7G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation.
- Poids moléculaire
- 31.64 kDa
- UniProt
- Q96RS0
- Pathways
- Mitotic G1-G1/S Phases, Regulation of Lipid Metabolism by PPARalpha, Ribonucleoprotein Complex Subunit Organization
-
