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OBFC2A Protein (AA 1-204, full length) (His-SUMO Tag)

OBFC2A Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5711666
  • Antigène Voir toutes OBFC2A Protéines
    OBFC2A (Oligonucleotide/oligosaccharide-Binding Fold Containing 2A (OBFC2A))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-204, full length
    Origine
    • 2
    • 1
    • 1
    • 1
    Humain
    Source
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette OBFC2A protéine est marqué à la His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    MNRVNDPLIF IRDIKPGLKN LNVVFIVLEI GRVTKTKDGH EVRSCKVADK TGSITISVWD EIGGLIQPGD IIRLTRGYAS MWKGCLTLYT GRGGELQKIG EFCMVYSEVP NFSEPNPDYR GQQNKGAQSE QKNNSMNSNM GTGTFGPVGN GVHTGPESRE HQFSHAGRSN GRGLINPQLQ GTASNQTVMT TISNGRDPRR AFKR
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product OBFC2A Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    OBFC2A (Oligonucleotide/oligosaccharide-Binding Fold Containing 2A (OBFC2A))
    Autre désignation
    SOSB2 (OBFC2A Produits)
    Synonymes
    OBFC2A Protein, SOSS-B2 Protein, SSB2 Protein, 4930434H03Rik Protein, 4930442A21Rik Protein, 4930488J04Rik Protein, 4933440J18Rik Protein, 5830411E10Rik Protein, AI852561 Protein, Nbp1 Protein, Obfc2a Protein, Ssb2 Protein, RGD1306658 Protein, nucleic acid binding protein 1 Protein, NABP1 Protein, Nabp1 Protein
    Sujet
    Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
    Poids moléculaire
    38.4 kDa
    UniProt
    Q96AH0
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