P4HTM Protein (AA 82-563) (His-SUMO Tag)
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- Antigène Voir toutes P4HTM Protéines
- P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 82-563
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette P4HTM protéine est marqué à la His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- VHYSNGDESS DPGPQHRAQG PGPEPTLGPL TRLEGIKVGH ERKVQLVTDR DHFIRTLSLK PLLFEIPGFL TDEECRLIIH LAQMKGLQRS QILPTEEYEE AMSTMQVSQL DLFRLLDQNR DGHLQLREVL AQTRLGNGWW MTPESIQEMY AAIKADPDGD GVLSLQEFSN MDLRDFHKYM RSHKAESSEL VRNSHHTWLY QGEGAHHIMR AIRQRVLRLT RLSPEIVELS EPLQVVRYGE GGHYHAHVDS GPVYPETICS HTKLVANESV PFETSCRQVS PNWGLPSILR PGTPMTQAQP CTVGVPLGMG PGDHWVIPVS PWEHPQLGTC SVPPLPYSYM TVLFYLNNVT GGGETVFPVA DNRTYDEMSL IQDDVDLRDT RRHCDKGNLR VKPQQGTAVF WYNYLPDGQG WVGDVDDYSL HGGCLVTRGT KWIANNWINV DPSRARQALF QQEMARLARE GGTDSQPEWA LDRAYRDARV EL
- Purification
- SDS-PAGE
- Pureté
- > 90 %
- Top Product
- Discover our top product P4HTM Protéine
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Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM) (AA 1-563) protein (GST tag)
P4HTM Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AP, AA
Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM) (AA 82-502) protein (His tag)Crystallography grade P4HTM Origine: Humain Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM) (AA 83-503) protein (His tag)Crystallography grade P4HTM Origine: Souris Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM) (AA 1-503) protein (Strep Tag)Crystallography grade P4HTM Origine: Souris Hôte: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM) (AA 1-502) protein (Strep Tag)Crystallography grade P4HTM Origine: Humain Hôte: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Antigène
- P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))
- Autre désignation
- P4HTM (P4HTM Produits)
- Synonymes
- Ph-4 Protein, RGD1311848 Protein, EGLN4 Protein, HIFPH4 Protein, P4H-TM Protein, PH-4 Protein, PH4 Protein, PHD4 Protein, 4933406E20Rik Protein, AI853847 Protein, BB128974 Protein, prolyl 4-hydroxylase, transmembrane Protein, prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) Protein, shisa family member 5 Protein, P4htm Protein, P4HTM Protein, SHISA5 Protein
- Sujet
- Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
- Poids moléculaire
- 70.51 kDa
- UniProt
- Q9NXG6
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