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METTL11A Protein (AA 1-223, full length) (His-SUMO Tag)

METTL11A Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5711881
  • Antigène Voir toutes METTL11A Protéines
    METTL11A (Methyltransferase Like 11A (METTL11A))
    Type de proteíne
    Recombinant
    Attributs du protein
    full length, AA 1-223
    Origine
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 5
    • 4
    • 3
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette METTL11A protéine est marqué à la His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    MTSEVIEDEK QFYSKAKTYW KQIPPTVDGM LGGYGHISSI DINSSRKFLQ RFLREGPNKT GTSCALDCGA GIGRITKRLL LPLFREVDMV DITEDFLVQA KTYLGEEGKR VRNYFCCGLQ DFTPEPDSYD VIWIQWVIGH LTDQHLAEFL RRCKGSLRPN GIIVIKDNMA QEGVILDDVD SSVCRDLDVV RRIICSAGLS LLAEERQENL PDEIYHVYSF ALR
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product METTL11A Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    METTL11A (Methyltransferase Like 11A (METTL11A))
    Autre désignation
    NTM1A (METTL11A Produits)
    Synonymes
    C9orf32 Protein, C11H9orf32 Protein, METTL11A Protein, NTM1A Protein, AD-003 Protein, HOMT1A Protein, NRMT Protein, 2610205E22Rik Protein, AL033331 Protein, AL033332 Protein, Mettl11a Protein, RGD1306582 Protein, mettl11a Protein, zgc:77488 Protein, N-terminal Xaa-Pro-Lys N-methyltransferase 1 Protein, NTMT1 Protein, Ntmt1 Protein, ntmt1 Protein
    Sujet
    Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by METTL11B-mediated monomethylation. Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1.
    Poids moléculaire
    41.4 kDa
    UniProt
    Q9BV86
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