ARL2 Protein (AA 19-184, partial) (GST tag)
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- Antigène Voir toutes ARL2 Protéines
- ARL2 (ADP-Ribosylation Factor-Like 2 (ARL2))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 19-184, partial
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette ARL2 protéine est marqué à la GST tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- LLMLGLDNAG KTTILKKFNG EDIDTISPTL GFNIKTLEHR GFKLNIWDVG GQKSLRSYWR NYFESTDGLI WVVDSADRQR MQDCQRELQS LLVEERLAGA TLLIFANKQD LPGALSSNAI REVLELDSIR SHHWCIQGCS AVTGENLLPG IDWLLDDISS RIFTAD
- Purification
- SDS-PAGE
- Pureté
- > 90 %
- Top Product
- Discover our top product ARL2 Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Antigène
- ARL2 (ADP-Ribosylation Factor-Like 2 (ARL2))
- Autre désignation
- ARL2 (ARL2 Produits)
- Synonymes
- arfl2 Protein, MGC75676 Protein, ARFL2 Protein, 2610009M23Rik Protein, AI115441 Protein, AW553335 Protein, ADP ribosylation factor like GTPase 2 Protein, ADP-ribosylation factor-like 2 Protein, ADP-ribosylation factor like GTPase 2 Protein, arl2 Protein, ARL2 Protein, Arl2 Protein
- Sujet
- Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassbly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassbly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca2+-dependent release of acetylcholine. Required for normal progress through the cell cycle.
- Poids moléculaire
- 46.1 kDa
- UniProt
- P36404
- Pathways
- Cell-Cell Junction Organization, Maintenance of Protein Location
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