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ARL2 Protein (AA 19-184, partial) (GST tag)

ARL2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5712127
  • Antigène Voir toutes ARL2 Protéines
    ARL2 (ADP-Ribosylation Factor-Like 2 (ARL2))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 19-184, partial
    Origine
    • 5
    • 1
    • 1
    • 1
    Humain
    Source
    • 4
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette ARL2 protéine est marqué à la GST tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    LLMLGLDNAG KTTILKKFNG EDIDTISPTL GFNIKTLEHR GFKLNIWDVG GQKSLRSYWR NYFESTDGLI WVVDSADRQR MQDCQRELQS LLVEERLAGA TLLIFANKQD LPGALSSNAI REVLELDSIR SHHWCIQGCS AVTGENLLPG IDWLLDDISS RIFTAD
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product ARL2 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    ARL2 (ADP-Ribosylation Factor-Like 2 (ARL2))
    Autre désignation
    ARL2 (ARL2 Produits)
    Synonymes
    arfl2 Protein, MGC75676 Protein, ARFL2 Protein, 2610009M23Rik Protein, AI115441 Protein, AW553335 Protein, ADP ribosylation factor like GTPase 2 Protein, ADP-ribosylation factor-like 2 Protein, ADP-ribosylation factor like GTPase 2 Protein, arl2 Protein, ARL2 Protein, Arl2 Protein
    Sujet
    Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassbly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassbly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca2+-dependent release of acetylcholine. Required for normal progress through the cell cycle.
    Poids moléculaire
    46.1 kDa
    UniProt
    P36404
    Pathways
    Cell-Cell Junction Organization, Maintenance of Protein Location
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