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PSMA7 Protein (AA 44-275, partial) (GST tag)

PSMA7 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5712137
  • Antigène Voir toutes PSMA7 Protéines
    PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 44-275, partial
    Origine
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 7
    • 4
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette PSMA7 protéine est marqué à la GST tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    TTIAGVVYKD GIVLGADTRA TEGMVVADKN CSKIHFISPN IYCCGAGTAA DTDMTTQLIS SNLELHSLST GRLPRVVTAN RMLKQMLFRY QGYIGAALVL GGVDVTGPHL YSIYPHGSTD KLPYVTMGSG SLAAMAVFED KFRPDMEEEE AKNLVSEAIA AGIFNDLGSG SNIDLCVISK NKLDFLRPYT VPNKKGTRLG RYRCEKGTTA VLTEKITPLE IEVLEETVQT MD
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product PSMA7 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
    Autre désignation
    PSA7 (PSMA7 Produits)
    Synonymes
    C6 Protein, HSPC Protein, RC6-1 Protein, XAPC7 Protein, C6-I Protein, DDBDRAFT_0185059 Protein, DDBDRAFT_0217080 Protein, DDB_0185059 Protein, DDB_0217080 Protein, hspc Protein, rc6-1 Protein, xapc7 Protein, psma7 Protein, psma4-B Protein, proteasome subunit alpha 7 Protein, proteasome (prosome, macropain) subunit, alpha type 7 Protein, 20S proteasome subunit alpha-7 Protein, proteasome subunit alpha 7 S homeolog Protein, proteasome subunit alpha 7 L homeolog Protein, PSMA7 Protein, Psma7 Protein, psmA7 Protein, psma7 Protein, psma7.S Protein, psma7.L Protein
    Sujet
    The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH . The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with AP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.
    Poids moléculaire
    52.5 kDa
    UniProt
    O14818
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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