RPA4 Protein (AA 1-260, partial) (His tag)

N° du produit ABIN5713010

Détail du produit

Antigène: RPA4 (Replication Protein A4, 30kDa (RPA4))

Type de proteíne: Recombinant

Attributs du protein: AA 1-260, partial

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette RPA4 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MSKSGFGSYG SISAADGASG GSDQLCERDA TPAIKTQRPK VRIQDVVPCN VNQLLSSTVF DPVFKVRGII VSQVSIVGVI RGAEKASNHI CYKIDDMTAK PIEARQWFGR EKVKQVTPLS VGVYVKVFGI LKCPTGTKSL EVLKIHVLED MNEFTVHILE TVNAHMMLDK ARRDTTVESV PVSPSEVNDA GDNDESHRNF IQDEVLRLIH ECPHQEGKSI HELRAQLCDL SVKAIKEAID YLTVEGHIYP TVDREHFKSA

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: RPA4 (Replication Protein A4, 30kDa (RPA4))

Autre désignation: RFA4 (RPA4 Produits)

Synonymes: HSU24186 Protein, replication protein A4 Protein, RPA4 Protein

Sujet: As part of the alternative replication protein A complex, aRPA, binds single-stranded DNA and probably plays a role in DNA repair. Compared to the RPA2-containing, canonical RPA complex, may not support chromosomal DNA replication and cell cycle progression through S-phase. The aRPA may not promote efficient priming by DNA polymerase alpha but could support DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.

Poids moléculaire: 32.8 kDa

UniProt: Q13156

Pathways: Mitotic G1-G1/S Phases, DNA Replication