ARNT Protein (AA 1-474, partial) (His tag)

N° du produit ABIN5713256

Détail du produit

Antigène: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Type de proteíne: Recombinant

Attributs du protein: partial, AA 1-474

Origine: Humain

Source: Levure

Purification/Conjugué: Cette ARNT protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MAATTANPEM TSDVPSLGPA IASGNSGPGI QGGGAIVQRA IKRRPGLDFD DDGEGNSKFL RCDDDQMSND KERFARSDDE QSSADKERLA RENHSEIERR RRNKMTAYIT ELSDMVPTCS ALARKPDKLT ILRMAVSHMK SLRGTGNTST DGSYKPSFLT DQELKHLILE AADGFLFIVS CETGRVVYVS DSVTPVLNQP QSEWFGSTLY DQVHPDDVDK LREQLSTSEN ALTGRILDLK TGTVKKEGQQ SSMRMCMGSR RSFICRMRCG SSSVDPVSVN RLSFVRNRCR NGLGSVKDGE PHFVVVHCTG YIKAWPPAGV SLPDDDPEAG QGSKFCLVAI GRLQVTSSPN CTDMSNVCQP TEFISRHNIE GIFTFVDHRC VATVGYQPQE LLGKNIVEFC HPEDQQLLRD SFQQVVKLKG QVLSVMFRFR SKNQEWLWMR TSSFTFQNPY SDEIEYIICT NTNVKNSSQE PRPT

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Autre désignation: ARNT (ARNT Produits)

Synonymes: HIF-1-beta Protein, HIF-1beta Protein, HIF1-beta Protein, HIF1B Protein, HIF1BETA Protein, TANGO Protein, bHLHe2 Protein, D3Ertd557e Protein, Drnt Protein, ESTM42 Protein, Hif1b Protein, W08714 Protein, mKIAA4051 Protein, Arnt1 Protein, ARNT Protein, zgc:136664 Protein, arnt1 Protein, hif1b Protein, tango Protein, xArnt Protein, hif1beta Protein, hif-1beta Protein, arnt.2 Protein, MGC68805 Protein, aryl hydrocarbon receptor nuclear translocator Protein, aryl hydrocarbon receptor nuclear translocator S homeolog Protein, ARNT Protein, Arnt Protein, arnt Protein, arnt.S Protein

Sujet: Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.

Poids moléculaire: 54.83 kDa

UniProt: P27540

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, L'effet Warburg