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CYR61 Protein (AA 25-379) (His tag)

CYR61 Origine: Souris Hôte: Levure Recombinant > 90 % SDS
N° du produit ABIN5713392
  • Antigène Voir toutes CYR61 Protéines
    CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 25-379
    Origine
    • 9
    • 4
    • 1
    • 1
    • 1
    Souris
    Source
    • 5
    • 4
    • 3
    • 2
    • 2
    Levure
    Purification/Conjugué
    Cette CYR61 protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    TCPAACHCPL EAPKCAPGVG LVRDGCGCCK VCAKQLNEDC SKTQPCDHTK GLECNFGASS TALKGICRAQ SEGRPCEYNS RIYQNGESFQ PNCKHQCTCI DGAVGCIPLC PQELSLPNLG CPNPRLVKVS GQCCEEWVCD EDSIKDSLDD QDDLLGLDAS EVELTRNNEL IAIGKGSSLK RLPVFGTEPR VLFNPLHAHG QKCIVQTTSW SQCSKSCGTG ISTRVTNDNP ECRLVKETRI CEVRPCGQPV YSSLKKGKKC SKTKKSPEPV RFTYAGCSSV KKYRPKYCGS CVDGRCCTPL QTRTVKMRFR CEDGEMFSKN VMMIQSCKCN YNCPHPNEAS FRLYSLFNDI HKFRD
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product CYR61 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
    Autre désignation
    CYR61 (CYR61 Produits)
    Synonymes
    CCN1 Protein, GIG1 Protein, IGFBP10 Protein, ccn1 Protein, gig1 Protein, Xcyr61 Protein, igfbp10 Protein, MGC69281 Protein, MGC69539 Protein, cyr61-l2 Protein, zgc:158158 Protein, CYR61 Protein, AI325051 Protein, Igfbp10 Protein, cysteine rich angiogenic inducer 61 Protein, cysteine-rich, angiogenic inducer, 61 Protein, cysteine-rich, angiogenic inducer, 61 like 2 Protein, cysteine rich protein 61 Protein, cysteine rich angiogenic inducer 61 S homeolog Protein, CYR61 Protein, Cyr61 Protein, cyr61 Protein, cyr61l2 Protein, cyr61.S Protein
    Sujet
    Promotes cell proliferation, chotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix rodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5 . CYR61-mediated gene regulation is dependent on heparin-binding . Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1 . Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-1/beta-5 and cell proliferation through integrin alpha-v/beta-3 .
    Poids moléculaire
    41.14 kDa
    UniProt
    P18406
    Pathways
    Positive Regulation of Endopeptidase Activity, Growth Factor Binding
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