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NDUFS6 Protein (AA 28-124) (His tag)
NDUFS6
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 % by SDS - PAGE
SDS
N° du produit ABIN5853085
Détail du produit
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Antigène
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NDUFS6
(NADH Dehydrogenase (Ubiquinone) Fe-S Protein 6, 13kDa (NADH-Coenzyme Q Reductase) (NDUFS6))
Type de proteíne
Recombinant
Attributs du protein
AA 28-124
Origine
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Humain
Source
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Escherichia coli (E. coli)
Purification/Conjugué
Cette NDUFS6 protéine est marqué à la His tag.
Application
SDS-PAGE (SDS)
Séquence
MGSSHHHHHH SSGLVPRGSH MGSFGVRVSP TGEKVTHTGQ VYDDKDYRRI RFVGRQKEVN ENFAIDLIAE QPVSEVETRV IACDGGGGAL GHPKVYINLD KETKTGTCGY CGLQFRQHHH
Pureté
> 90 % by SDS - PAGE
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 30 % glycerol, 1 mM DTT
Stock
4 °C,-20 °C,-80 °C
Stockage commentaire
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Détail du antigène
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Antigène
NDUFS6
(NADH Dehydrogenase (Ubiquinone) Fe-S Protein 6, 13kDa (NADH-Coenzyme Q Reductase) (NDUFS6))
Autre désignation
NDuFS6 (NDUFS6 Produits )
Synonymes
BC059730 Protein, IP13 Protein, Ip13dis Protein, Ndub13 Protein, RATIp13dis Protein, CI-13kA Protein, CI-13kD-A Protein, CI13KDA Protein, NADH dehydrogenase (ubiquinone) Fe-S protein 6 Protein, NADH:ubiquinone oxidoreductase subunit S6 Protein, Ndufs6 Protein, NDUFS6 Protein
Sujet
NDuFS6 is a subunit of the NADH:ubiquinone oxidoreductase (complex I), which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit is one of seven subunits in the iron-sulfur protein fraction. Mutations cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders. Recombinant human NDuFS6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques
Poids moléculaire
13.2kDa (120aa), confirmed by MALDI-TOF
NCBI Accession
NP_004544
UniProt
O75380
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