UPRT Protein (AA 1-309) (His tag)
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- Antigène Voir toutes UPRT Protéines
- UPRT (Uracil phosphoribosyltransferase (FUR1) Homolog (UPRT))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-309
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette UPRT protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- MGSSHHHHHH SSGLVPRGSH MGSMATELQC PDSMPCHNQQ VNSASTPSPE QLRPGDLILD HAGGNRASRA KVILLTGYAH SSLPAELDSG ACGGSSLNSE GNSGSGDSSS YDAPAGNSFL EDCELSRQIG AQLKLLPMND QIRELQTIIR DKTASRGDFM FSADRLIRLV VEEGLNQLPY KECMVTTPTG YKYEGVKFEK GNCGVSIMRS GEAMEQGLRD CCRSIRIGKI LIQSDEETQR AKVYYAKFPP DIYRRKVLLM YPILSTGNTV IEAVKVLIEH GVQPSVIILL SLFSTPHGAK SIIQEFPEIT ILTTEVHPVA PTHFGQKYFG TD
- Pureté
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product UPRT Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 20 % glycerol, 1 mM DTT
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Antigène
- UPRT (Uracil phosphoribosyltransferase (FUR1) Homolog (UPRT))
- Autre désignation
- uPRT (UPRT Produits)
- Synonymes
- Gm774 Protein, FUR1 Protein, UPP Protein, uracil phosphoribosyltransferase Protein, uracil phosphoribosyltransferase homolog Protein, Uprt Protein, UPRT Protein
- Sujet
- UPRT is a uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (uMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer. Recombinant human uPRT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Poids moléculaire
- 36.2 kDa (332aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_659489
- UniProt
- Q96BW1
- Pathways
- Ribonucleoside Biosynthetic Process
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