QKI Protein (AA 1-341) (His tag)
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- Antigène Voir toutes QKI Protéines
- QKI (Protein Quaking (QKI))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-341
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette QKI protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- MGSSHHHHHH SSGLVPRGSH MGSMVGEMET KEKPKPTPDY LMQLMNDKKL MSSLPNFCGI FNHLERLLDE EISRVRKDMY NDTLNGSTEK RSAELPDAVG PIVQLQEKLY VPVKEYPDFN FVGRILGPRG LTAKQLEAET GCKIMVRGKG SMRDKKKEEQ NRGKPNWEHL NEDLHVLITV EDAQNRAEIK LKRAVEEVKK LLVPAAEGED SLKKMQLMEL AILNGTYRDA NIKSPALAFS LAATAQAAPR IITGPAPVLP PAALRTPTPA GPTIMPLIRQ IQTAVMPNGT PHPTAAIVPP GPEAGLIYTP YEYPYTLAPA TSILEYPIEP SGVLGAVATK VRRHDMRVHP YQRIVTADRA ATGN
- Pureté
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product QKI Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.2M NaCl, 50 % glycerol, 2 mM DTT
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Antigène
- QKI (Protein Quaking (QKI))
- Autre désignation
- QKI (QKI Produits)
- Synonymes
- Hqk Protein, QK Protein, QK1 Protein, QK3 Protein, hqkI Protein, 1110003F05Rik Protein, 1500005P18 Protein, QkI Protein, l(17)-1Wis Protein, l17Wis1 Protein, Qki Protein, CQKI Protein, QKI-5 Protein, PqkI Protein, BqkI Protein, qk Protein, qk1 Protein, quaking Protein, Xqua Protein, qki Protein, EQKI Protein, EqkI Protein, QKI, KH domain containing RNA binding Protein, quaking Protein, QKI, KH domain containing, RNA binding S homeolog Protein, QKI, KH domain containing, RNA binding L homeolog Protein, QKI Protein, Qk Protein, qki.S Protein, qki.L Protein, Qki Protein
- Sujet
- Protein quaking isoform HQK-5, also known as QKI, is an RNA-binding protein that regulates pre-mRNA splicing, export of mRNAs from the nucleus, protein translation, and mRNA stability. It is involved in myelinization and oligodendrocyte differentiation, and it may play a role in schizophrenia. Defects or deletions in the QKI are associated with astrocytic tumors and may be involved in the pathogenesis of schizophrenia. Recombinant human QKI protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Poids moléculaire
- 40.1 kDa (364aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_006766
- UniProt
- Q96PU8
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