LECT1 Protein (AA 214-333) (His tag)

N° du produit ABIN5853515

Détail du produit

Antigène: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Type de proteíne: Recombinant

Attributs du protein: AA 214-333

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette LECT1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSREVVRKI VPTTTKRPHS GPRSNPGAGR LNNETRPSVQ EDSQAFNPDN PYHQEGESMT FDPRLDHEGI CCIECRRSYT HCQKICEPLG GYYPWPYNYQ GCRSACRVIM PCSWWVARIL GMV

Pureté: > 85 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Denatured

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M uREA, 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Autre désignation: LECT1 (LECT1 Produits)

Synonymes: chm1 Protein, chm-i Protein, bricd3 Protein, MGC53801 Protein, MGC82444 Protein, chondromodulin-I Protein, Lect1 Protein, BRICD3 Protein, CHM-I Protein, CHM1 Protein, MYETS1 Protein, Bricd3 Protein, ChM-I Protein, Chm-1 Protein, chondromodulin L homeolog Protein, leukocyte cell derived chemotaxin 1 Protein, chondromodulin Protein, cnmd.L Protein, lect1 Protein, CNMD Protein, cnmd Protein, Cnmd Protein

Sujet: LECT1 is a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. Recombinant human LECT1 protein, fused to His-tag at N-terminus, was expressed in E.coli

Poids moléculaire: 16.2kDa (143aa)

NCBI Accession: NP_001011705

UniProt: O75829