GAD Protein (AA 1-224) (His tag)
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- Antigène Voir toutes GAD (GAD1) Protéines
- GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-224
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette GAD protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- MGSSHHHHHH SSGLVPRGSH MGSMASSTPS SSATSSNAGA DPNTTNLRPT TYDTWCGVAH GCTRKLGLKI CGFLQRTNSL EEKSRLVSAF KERQSSKNLL SCENSDRDAR FRRTETDFSN LFARDLLPAK NGEEQTVQFL LEVVDILLNY VRKTFDRSTK VLDFHHPHQL LEGMEGFNLE LSDHPESLEQ ILVDCRDTLK YGVRTGHPRF FNQLSTGLDI IGLAGEWLTS TANTNMPSDM RECWLLR
- Pureté
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product GAD1 Protéine
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Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1) (AA 1-594) protein (GST tag)
GAD1 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1) (AA 1-594) protein (His tag)Crystallography grade GAD1 Origine: Humain Hôte: Tobacco (Nicotiana tabacum) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1) (AA 1-593) protein (His tag)Crystallography grade GAD1 Origine: Souris Hôte: Tobacco (Nicotiana tabacum) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1) proteinGAD1 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1) protein (Myc-DYKDDDDK Tag)GAD1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol, 0.4M urea
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Antigène
- GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
- Autre désignation
- GAD1 (GAD1 Produits)
- Sujet
- GAD1 is one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. It is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This protien may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. Recombinant human GAD1 protein, fused to His-tag at N-terminus, was expressed in E.coli .
- Poids moléculaire
- 27.7 kDa (247 aa)
- NCBI Accession
- NP_038473
- UniProt
- Q99259
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