M6PR Protein (AA 27-185) (His tag)

N° du produit ABIN5853696

Détail du produit

Antigène: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Type de proteíne: Recombinant

Attributs du protein: AA 27-185

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette M6PR protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSTEEKTCD LVGEKGKESE KELALVKRLK PLFNKSFEST VGQGSDTYIY IFRVCREAGN HTSGAGLVQI NKSNGKETVV GRLNETHIFN GSNWIMLIYK GGDEYDNHCG KEQRRAVVMI SCNRHTLADN FNPVSEERGK VQDCFYLFEM DSSLACSPEI SH

Pureté: > 85 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Autre désignation: M6PR (M6PR Produits)

Synonymes: CD222 Protein, CIMPR Protein, M6P-R Protein, MPR1 Protein, MPRI Protein, CD-MPR Protein, MPR 46 Protein, MPR-46 Protein, MPR46 Protein, SMPR Protein, Mpr46 Protein, CDMPR Protein, m6pr Protein, MGC68896 Protein, MGC130765 Protein, zgc:77757 Protein, wu:fj81h11 Protein, MGC89423 Protein, M6PR Protein, mprd Protein, C16orf27 Protein, GNPTAG Protein, LP2537 Protein, RJD9 Protein, insulin like growth factor 2 receptor Protein, mannose-6-phosphate receptor, cation dependent Protein, mannose-6-phosphate receptor (cation dependent) L homeolog Protein, mannose-6-phosphate receptor (cation dependent) Protein, mannose-6-phosphate receptor (cation dependent) S homeolog Protein, Cation-dependent mannose-6-phosphate receptor Protein, N-acetylglucosamine-1-phosphate transferase gamma subunit Protein, IGF2R Protein, M6PR Protein, M6pr Protein, m6pr.L Protein, m6pr Protein, m6pr.S Protein, Ethha_1678 Protein, mprd Protein, GNPTG Protein

Sujet: M6PR is a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. This protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. Recombinant human M6PR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques..

Poids moléculaire: 20.3kDa (182aa) confirmed by MALDI-TOF

NCBI Accession: NP_002346

UniProt: P20645