PRKRA Protein (AA 1-313) (His tag)

N° du produit ABIN5853828

Détail du produit

Antigène: PRKRA (Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA))

Type de proteíne: Recombinant

Attributs du protein: AA 1-313

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PRKRA protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMSQSRHR AEAPPLERED SGTFSLGKMI TAKPGKTPIQ VLHEYGMKTK NIPVYECERS DVQIHVPTFT FRVTVGDITC TGEGTSKKLA KHRAAEAAIN ILKANASICF AVPDPLMPDP SKQPKNQLNP IGSLQELAIH HGWRLPEYTL SQEGGPAHKR EYTTICRLES FMETGKGASK KQAKRNAAEK FLAKFSNISP ENHISLTNVV GHSLGCTWHS LRNSPGEKIN LLKRSLLSIP NTDYIQLLSE IAKEQGFNIT YLDIDELSAN GQYQCLAELS TSPITVCHGS GISCGNAQSD AAHNALQYLK IIAERK

Pureté: > 80 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.2M NaCl, 50 % glycerol, 2  mM DTT, 1  mM EDTA

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: PRKRA (Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA))

Autre désignation: PRKRA (PRKRA Produits)

Synonymes: PRKRA Protein, AV120107 Protein, PRK Protein, Pact Protein, RAX Protein, lear Protein, DYT16 Protein, PACT Protein, im:7151758 Protein, zgc:162619 Protein, dyt16 Protein, pact Protein, prkra-a Protein, prkra-b Protein, rax Protein, rbpa Protein, protein activator of interferon induced protein kinase EIF2AK2 Protein, protein kinase, interferon inducible double stranded RNA dependent activator Protein, protein kinase, interferon-inducible double stranded RNA dependent activator Protein, protein activator of interferon induced protein kinase EIF2AK2 L homeolog Protein, PRKRA Protein, Prkra Protein, prkra Protein, prkra.L Protein

Sujet: PRKRA is a protein kinase activated by double-stranded RNA which mediates the effects of interferon in response to viral infection. Mutations in this gene have been associated with dystonia. Alternative splicing results in multiple transcript variants. Recombinant human PRKRA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 36.8 kDa (336aa) confirmed by MALDI-TOF

NCBI Accession: NP_003681

UniProt: O75569

Pathways: Regulatory RNA Pathways