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IL28B Protein (AA 22-196) (His tag)

IL28B Origine: Humain Hôte: Baculovirus infected Insect Cells Recombinant > 85 % by SDS - PAGE. SDS
N° du produit ABIN5854225
  • Antigène Voir toutes IL28B Protéines
    IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 22-196
    Origine
    • 9
    • 3
    • 1
    Humain
    Source
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Baculovirus infected Insect Cells
    Purification/Conjugué
    Cette IL28B protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    VPVARLRGAL PDARGCHIAQ FKSLSPQELQ AFKRAKDALE ESLLLKDCKC RSRLFPRTWD LRQLQVRERP VALEAELALT LKVLEATADT DPALGDVLDQ PLHTLHHILS QLRACIQPQP TAGPRTRGRL HHWLHRLQEA PKKESPGCLE ASVTFNLFRL LTRDLNCVAS GDLCVHHHHH H
    Pureté
    > 85 % by SDS - PAGE.
    niveau d'endotoxine
    < 1.0 EU per 1 microgram of protein (determined by LAL method)
    Top Product
    Discover our top product IL28B Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    Liquid. In phosphate buffered saline (  pH 7.4) containing 20 % glycerol, 1  mM EDTA, 0.1  mM PMSF.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Antigène
    IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))
    Autre désignation
    IFNL3 (IL28B Produits)
    Synonymes
    Il28b Protein, IFL-1 Protein, IL-28B Protein, INF-alpha Protein, INF-lambda Protein, Il28 Protein, IL28B Protein, IL28C Protein, interferon, lambda 3 Protein, interferon lambda 3 Protein, Ifnl3 Protein, IFNL3 Protein
    Sujet
    IFNL3, also known as Interferon lambda-3, is a secreted protein which belongs to the IL-28/IL-29 family. It is a cytokine with immunomodulatory activity. It up-regulates MHC class I antigen expression. This protein displays potent antiviral activity and antitumor activity. It seems to signal through the Jak-STAT pathway. It also contributes to viral resistance and is known to be upregulated by interferons and by RNA virus infection. Recombinant human IFNL3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Poids moléculaire
    20.4kDa (181aa) 18-28kDa (SDS-PAGE under reducing conditions.)
    NCBI Accession
    NP_742151
    UniProt
    Q8IZI9
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