TACSTD2 Protein (AA 31-274) (His tag)

N° du produit ABIN5854731

Détail du produit

Antigène: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Type de proteíne: Recombinant

Attributs du protein: AA 31-274

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette TACSTD2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: ADPQDNCTCP TNKMTVCSPD GPGGRCQCRA LGSGMAVDCS TLTSKCLLLK ARMSAPKNAR TLVRPSEHAL VDNDGLYDPD CDPEGRFKAR QCNQTSVCWC VNSVGVRRTD KGDLSLRCDE LVRTHHILID LRHRPTAGAF NHSDLDAELR RLFRERYRLH PKFVAAVHYE QPTIQIELRQ NTSQKAAGDV DIGDAAYYFE RDIKGESLFQ GRGGLDLRVR GEPLQVERTL IYYLDEIPPK FSMKRLTHHH HHH

Pureté: > 95 % by SDS - PAGE

niveau d'endotoxine: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Autre désignation: TACSTD2 (TACSTD2 Produits)

Synonymes: EGP-1 Protein, EGP1 Protein, GA733-1 Protein, GA7331 Protein, GP50 Protein, M1S1 Protein, TROP2 Protein, C80403 Protein, Ly97 Protein, Prp1 Protein, tumor associated calcium signal transducer 2 Protein, tumor-associated calcium signal transducer 2 Protein, TACSTD2 Protein, Tacstd2 Protein

Sujet: TACSTD2, also known as tumor-associated calcium signal transducer 2, is an identified cell surface glycoprotein highly expressed by human carcinomas. It is detected in normal kidney, lung, ovary and testis, similarly to the human gene. It is undetectable in undifferentiated spindle cell carcinomas, this suggests a preferential expression at early stages of tumor progression. Its inhibition suppresses the proliferation and invasion of laryngeal carcinoma cells via the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway. Recombinant human TACSTD2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 28.6kDa (253aa) 28-40kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_002344

UniProt: P09758