CNTF Receptor alpha Protein (AA 23-342) (His tag)
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- Antigène Voir toutes CNTF Receptor alpha (CNTFR) Protéines
- CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 23-342
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Origine
- Rat
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Source
- Baculovirus infected Insect Cells
- Purification/Conjugué
- Cette CNTF Receptor alpha protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- QKHSPQEAPH VQYERLGTDV TLPCGTASWD AAVTWRVNGT DLAPDLLNGS QLILRSLELG HSGLYACFHR DSWHLRHQVL LHVGLPPREP VLSCRSNTYP KGFYCSWHLS APTYIPNTFN VTVLHGSKMM VCEKDPALKN RCHIRYMHLF STIKYKVSIS VSNALGHNTT AITFDEFTIV KPDPPENVVA RPVPSNPRRL EVTWQTPSTW PDPESFPLKF FLRYRPLILD QWQHVELSNG TAHTITDAYA GKEYIIQVAA KDNEIGTWSD WSVAAHATPW TEEPRHLTTE AQAPETTTST TSSLAPPPTT KICDPGELSS LEHHHHHH
- Pureté
- > 90 % by SDS - PAGE
- niveau d'endotoxine
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product CNTFR Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Antigène
- CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))
- Autre désignation
- Cntfr (CNTFR Produits)
- Synonymes
- CNTFR-alpha Protein, CNTFRALPHA Protein, Cntfralpha Protein, cb549 Protein, fj33e02 Protein, sb:cb549 Protein, wu:fj33e02 Protein, si:bz76a6.1 Protein, si:dz248f2.1 Protein, si:rp71-76a6.1 Protein, ciliary neurotrophic factor receptor Protein, ciliary neurotrophic factor receptor L homeolog Protein, CNTFR Protein, cntfr.L Protein, Cntfr Protein, cntfr Protein
- Sujet
- Cntfr, also known as ciliary neurotrophic factor receptor subunit alpha, is a member of the type 1 cytokine receptor family. It mediates the biological action of CNTF. CNTF is a polypeptide hormone that supports the survival of neurons of the peripheral sensory, sympathetic, and ciliary ganglia at various stages in their development. CNTFR and its cognate ligand support the survival of neurons. The CNTF receptor complex is most closely related to, and shares subunits with the receptor complexes for interleukin-6 and leukemia inhibitory factor. The specificity conferring alpha subunit of the CNTF complex (CNTFR alpha), is extremely well conserved across species, and has a distribution localized predominantly to the nervous system and skeletal muscle. Recombinant rat Cntfr, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Poids moléculaire
- 36.9kDa (328aa) 40-57KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_001003929
- UniProt
- Q08406
- Pathways
- Signalistation JAK/STAT, Feeding Behaviour
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