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Kallikrein 5 Protein (KLK5) (AA 67-293) (His tag)

KLK5 Origine: Humain Hôte: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE SDS
N° du produit ABIN5854782
  • Antigène Voir toutes Kallikrein 5 (KLK5) Protéines
    Kallikrein 5 (KLK5)
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 67-293
    Origine
    • 7
    • 3
    Humain
    Source
    • 4
    • 3
    • 2
    • 1
    Baculovirus infected Insect Cells
    Purification/Conjugué
    Cette Kallikrein 5 protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    ADLIINGSDC DMHTQPWQAA LLLRPNQLYC GAVLVHPQWL LTAAHCRKKV FRVRLGHYSL SPVYESGQQM FQGVKSIPHP GYSHPGHSND LMLIKLNRRI RPTKDVRPIN VSSHCPSAGT KCLVSGWGTT KSPQVHFPKV LQCLNISVLS QKRCEDAYPR QIDDTMFCAG DKAGRDSCQG DSGGPVVCNG SLQGLVSWGD YPCARPNRPG VYTNLCKFTK WIQETIQANS HHHHHH
    Pureté
    > 95 % by SDS - PAGE
    niveau d'endotoxine
    < 1.0 EU per 1 microgram of protein (determined by LAL method)
    Top Product
    Discover our top product KLK5 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Antigène
    Kallikrein 5 (KLK5)
    Autre désignation
    KLK5 (KLK5 Produits)
    Synonymes
    KLK-L2 Protein, KLKL2 Protein, SCTE Protein, 1110030O19Rik Protein, KAL Protein, KALA Protein, Klk1 Protein, Klk5 Protein, RATKALA Protein, kallikrein related peptidase 5 Protein, kallikrein related-peptidase 5 Protein, kallikrein 5-like Protein, KLK5 Protein, Klk5 Protein, Klk5l Protein
    Sujet
    KLK5, also known as kallikrein-5, is one of the newly identified members of the kallikrein gene family, which is a subgroup of the serine protease enzyme family. It is highly expressed in skin, mammary gland and testis. KLK5 has been suggested to regulate cell shedding (desquamation) in conjunction with KLK7 and KLK14, given its ability to degrade proteins which form the extracellular component of cell junctions in the stratum corneum. It is proposed that KLK5 regulates this process since it is able to self-activate in addition to activating KLK7 and KLK14. Recombinant human KLK5, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Poids moléculaire
    26.2kDa (236aa) 28-40kDa (SDS-PAGE under reducing conditions)
    NCBI Accession
    NP_001070960
    UniProt
    Q9Y337
    Pathways
    Système du Complément, Regulation of G-Protein Coupled Receptor Protein Signaling
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