CEACAM5 Protein (AA 35-685) (His tag)

N° du produit ABIN7529361

Détail du produit

Antigène: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Type de proteíne: Recombinant

Attributs du protein: AA 35-685

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette CEACAM5 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: KLTIESTPFN VAEGKEVLLL VHNLPQHLFG YSWYKGERVD GNRQIIGYVI GTQQATPGPA YSGREIIYPN ASLLIQNIIQ NDTGFYTLHV IKSDLVNEEA TGQFRVYPEL PKPSISSNNS KPVEDKDAVA FTCEPETQDA TYLWWVNNQS LPVSPRLQLS NGNRTLTLFN VTRNDTASYK CETQNPVSAR RSDSVILNVL YGPDAPTISP LNTSYRSGEN LNLSCHAASN PPAQYSWFVN GTFQQSTQEL FIPNITVNNS GSYTCQAHNS DTGLNRTTVT TITVYAEPPK PFITSNNSNP VEDEDAVALT CEPEIQNTTY LWWVNNQSLP VSPRLQLSND NRTLTLLSVT RNDVGPYECG IQNKLSVDHS DPVILNVLYG PDDPTISPSY TYYRPGVNLS LSCHAASNPP AQYSWLIDGN IQQHTQELFI SNITEKNSGL YTCQANNSAS GHSRTTVKTI TVSAELPKPS ISSNNSKPVE DKDAVAFTCE PEAQNTTYLW WVNGQSLPVS PRLQLSNGNR TLTLFNVTRN DARAYVCGIQ NSVSANRSDP VTLDVLYGPD TPIISPPDSS YLSGANLNLS CHSASNPSPQ YSWRINGIPQ QHTQVLFIAK ITPNNNGTYA CFVSNLATGR NNSIVKSITV SASGTSPGLS ALEHHHHHH

Pureté: > 95 % by SDS - PAGE

niveau d'endotoxine: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Autre désignation: CEACAM5 (CEACAM5 Produits)

Synonymes: CD66e Protein, CEA Protein, CEACAM5 Protein, CEACAM Protein, 1600029H12Rik Protein, Psg30 Protein, carcinoembryonic antigen related cell adhesion molecule 5 Protein, carcinoembryonic antigen Protein, carcinoembryonic antigen-related cell adhesion molecule 5 Protein, carcinoembryonic antigen-related cell adhesion molecule 8 Protein, carcinoembryonic antigen gene family Protein, CEACAM5 Protein, Ceacam5 Protein, LOC100409241 Protein, Cea Protein

Sujet: CEACAM5, as known as carcinoembryonic antigen-related cell adhesion molecule 5, is the large CEACAM subfamily of immunoglobulin superfamily. This protein can mediate cell to cell adhesion through homotypic and heterotypic interactions. It is restricted to the apical face of intestinal epithelial cells in the adult but is more diffuse during embryonic development and in tumors. Also, it is upregulated in a wide variety of human tumors and is a commonly used cancer marker. Recombinant human CEACAM5, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 72.3kDa (659aa) 70-150kDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_004354

UniProt: P06731