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BCAM Protein (AA 32-547) (hIgG-His-tag)
BCAM
Origine: Humain
Hôte: Baculovirus infected Insect Cells
Recombinant
> 90 % by SDS - PAGE
SDS
N° du produit ABIN5854904
Détail du produit
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Antigène
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BCAM
(Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))
Type de proteíne
Recombinant
Attributs du protein
AA 32-547
Origine
Toutes les origines à travers BCAM Protéines
Humain
Source
Toutes les sources à travers BCAM Protéines
Baculovirus infected Insect Cells
Purification/Conjugué
Cette BCAM protéine est marqué à la hIgG-His-tag.
Application
SDS-PAGE (SDS)
Séquence
EVRLSVPPLV EVMRGKSVIL DCTPTGTHDH YMLEWFLTDR SGARPRLASA EMQGSELQVT MHDTRGRSPP YQLDSQGRLV LAEAQVGDER DYVCVVRAGA AGTAEATARL NVFAKPEATE VSPNKGTLSV MEDSAQEIAT CNSRNGNPAP KITWYRNGQR LEVPVEMNPE GYMTSRTVRE ASGLLSLTST LYLRLRKDDR DASFHCAAHY SLPEGRHGRL DSPTFHLTLH YPTEHVQFWV GSPSTPAGWV REGDTVQLLC RGDGSPSPEY TLFRLQDEQE EVLNVNLEGN LTLEGVTRGQ SGTYGCRVED YDAADDVQLS KTLELRVAYL DPLELSEGKV LSLPLNSSAV VNCSVHGLPT PALRWTKDST PLGDGPMLSL SSITFDSNGT YVCEASLPTV PVLSRTQNFT LLVQGSPELK TAEIEPKADG SWREGDEVTL ICSARGHPDP KLSWSQLGGS PAEPIPGRQG WVSSSLTLKV TSALSRDGIS CEASNPHGNK RHVFHFGTVS PQTSQAVEPK SCDKTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGKH HHHHH
Pureté
> 90 % by SDS - PAGE
niveau d'endotoxine
< 1.0 EU per 1 microgram of protein (determined by LAL method)
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.5 mg/mL
Buffer
Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
Stock
4 °C,-20 °C,-80 °C
Stockage commentaire
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Détail du antigène
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Antigène
BCAM
(Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))
Autre désignation
BCAM (BCAM Produits )
Synonymes
cd239 Protein, msk19 Protein, MGC81012 Protein, LU Protein, prr2 Protein, zgc:154034 Protein, 1200005K12Rik Protein, B-CAM Protein, Gplu Protein, Lu Protein, AU Protein, CD239 Protein, MSK19 Protein, basal cell adhesion molecule (Lutheran blood group) Protein, basal cell adhesion molecule (Lutheran blood group) L homeolog Protein, basal cell adhesion molecule Protein, bcam Protein, bcam.L Protein, BCAM Protein, Bcam Protein
Sujet
BCAM, also known as Basal cell adhesion molecule isoform 1, is an immunoglobulin superfamily protein that arises from alternate splicing of the Lutheran blood group molecule. This protein is upregulated following malignant transformation of some cell types in vivo and in vitro, thus being a candidate molecule involved in tumor progression. Also, it interacts with integrin in sickle red cells, and may potentially play a role in vaso-occlusive episodes. Recombinant human BCAM, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Poids moléculaire
83.2kDa (755aa) 70-100kDa (SDS-PAGE under reducing conditions.)
NCBI Accession
NP_005572
UniProt
P50895
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