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SIRPB1 Protein (AA 30-371) (His tag)

SIRPB1 Origine: Humain Hôte: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
N° du produit ABIN5855169
  • Antigène Voir toutes SIRPB1 Protéines
    SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 30-371
    Origine
    • 12
    • 1
    Humain
    Source
    • 5
    • 2
    • 2
    • 2
    • 2
    Baculovirus infected Insect Cells
    Purification/Conjugué
    Cette SIRPB1 protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    EDELQVIQPE KSVSVAAGES ATLRCAMTSL IPVGPIMWFR GAGAGRELIY NQKEGHFPRV TTVSELTKRN NLDFSISISN ITPADAGTYY CVKFRKGSPD DVEFKSGAGT ELSVRAKPSA PVVSGPAVRA TPEHTVSFTC ESHGFSPRDI TLKWFKNGNE LSDFQTNVDP AGDSVSYSIH STARVVLTRG DVHSQVICEI AHITLQGDPL RGTANLSEAI RVPPTLEVTQ QPMRAENQAN VTCQVSNFYP RGLQLTWLEN GNVSRTETAS TLIENKDGTY NWMSWLLVNT CAHRDDVVLT CQVEHDGQQA VSKSYALEIS AHQKEHGSDI THEAALAPTA PLHHHHHH
    Pureté
    > 90 % by SDS - PAGE
    niveau d'endotoxine
    < 1.0 EU per 1ug of protein (determined by LAL method)
    Top Product
    Discover our top product SIRPB1 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Antigène
    SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))
    Autre désignation
    SIRPB1 (SIRPB1 Produits)
    Synonymes
    CD172b Protein, SIRP-BETA-1 Protein, SIRPB1 Protein, SIRPG Protein, signal regulatory protein beta 1 Protein, signal-regulatory protein beta-1 Protein, signal-regulatory protein beta-1 isoform 3 Protein, SIRPB1 Protein, LOC458036 Protein, LOC458430 Protein, LOC485809 Protein, LOC715912 Protein, LOC100458151 Protein
    Sujet
    SIRPB1, also known as signal-regulatory protein beta-1 isoform 1, is a type I transmembrane protein of SIRP superfamily. It is an immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein also participates in the recruitment of tyrosine kinase SYK. And it acts as an activating isoform of SIRP alpha molecules that recruit SHP-1 and SHP-2 protein tyrosine phosphatases and activate counterparts, whose engagement couples to protein tyrosine kinases. Recombinant human SIRPB1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Poids moléculaire
    38.0kDa (348aa) 40-57KDa (SDS-PAGE under reducing conditions.)
    NCBI Accession
    NP_006056
    UniProt
    O00241
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