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OSCAR Protein (AA 19-282) (His tag)

OSCAR Origine: Humain Hôte: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
N° du produit ABIN5855171
  • Antigène Voir toutes OSCAR Protéines
    OSCAR (Osteoclast Associated Receptor (OSCAR))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 19-282
    Origine
    • 6
    • 3
    Humain
    Source
    • 3
    • 3
    • 2
    • 1
    Baculovirus infected Insect Cells
    Purification/Conjugué
    Cette OSCAR protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    DITPSVPPAS YHPKPWLGAQ PATVVTPGVN VTLRCRAPQP AWRFGLFKPG EIAPLLFRDV SSELAEFFLE EVTPAQGGSY RCCYRRPDWG PGVWSQPSDV LELLVTEELP RPSLVALPGP VVGPGANVSL RCAGRLRNMS FVLYREGVAA PLQYRHSAQP WADFTLLGAR APGTYSCYYH TPSAPYVLSQ RSEVLVISWE GEGPEARPAS SAPGMQAPGP PPSDPGAQAP SLSSFRPRGL VLQPLLPQTQ DSWDPAPPPS DPGVHHHHHH
    Pureté
    > 90 % by SDS - PAGE
    niveau d'endotoxine
    < 1.0 EU per 1ug of protein (determined by LAL method)
    Top Product
    Discover our top product OSCAR Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Antigène
    OSCAR (Osteoclast Associated Receptor (OSCAR))
    Autre désignation
    OSCAR (OSCAR Produits)
    Synonymes
    OSCAR Protein, mOSCAR-M3 Protein, mOSCAR Protein, mOSCAR-M1 Protein, mOSCAR-M2 Protein, PIGR3 Protein, PIgR-3 Protein, RGD1559897 Protein, osteoclast associated, immunoglobulin-like receptor Protein, osteoclast-associated immunoglobulin-like receptor Protein, osteoclast associated receptor Protein, OSCAR Protein, LOC748876 Protein, Oscar Protein
    Sujet
    OSCAR, also known as osteoclast-associated immunoglobulin-like receptor isoform 6, is an activating receptor expressed by human myeloid cells. It is a receptor for surfactant protein D that activates TNF-alpha release from human CCR2+ inflammatory monocytes. It is an FcRgamma-associated receptor that is expressed by myeloid cells and is involved in antigen presentation and activation of human dendritic cells. Its expression is detected specifically in preosteoclasts or mature osteoclasts. It is upregulated on monocytes from rheumatoid arthritis (RA) patients with active disease, and these monocytes show an increased proosteoclastogenic potential. Recombinant human OSCAR, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Poids moléculaire
    29.2kDa (270aa) 40-57kDa (SDS-PAGE under reducing conditions)
    NCBI Accession
    NP_001269278
    UniProt
    Q8IYS5
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