IFNA7 Protein (AA 24-189) (His tag)

N° du produit ABIN5855176

Détail du produit

Antigène: IFNA7 (IFNa7) (Interferon, alpha 7 (IFNa7))

Type de proteíne: Recombinant

Attributs du protein: AA 24-189

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette IFNA7 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: ADPCDLPQTH SLRNRRALIL LAQMGRISPF SCLKDRHEFR FPEEEFDGHQ FQKTQAISVL HEMIQQTFNL FSTEDSSAAW EQSLLEKFST ELYQQLNDLE ACVIQEVGVE ETPLMNEDFI LAVRKYFQRI TLYLMEKKYS PCAWEVVRAE IMRSFSFSTN LKKGLRRKDH HHHHH

Pureté: > 90 % by SDS - PAGE

niveau d'endotoxine: < 1.0 EU per 1ug of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: IFNA7 (IFNa7) (Interferon, alpha 7 (IFNa7))

Autre désignation: IFNA7 (IFNa7 Produits)

Synonymes: CaIFN-alpha 7 Protein, Ifa7 Protein, IFN-alphaJ Protein, IFNA-J Protein, interferon, alpha 7 Protein, interferon alpha-7 Protein, interferon alpha 7 Protein, IFNA7 Protein, LOC741747 Protein, Ifna7 Protein

Sujet: IFNA7, also known as interferon alpha-7, is a member of the interferon family. Interferon promotes the production of two enzymes, protein kinase and oligoadenylate synthetase. They allow the cells to communicate with the protective barrier of the immune system to eradicate pathogens or tumors. IFNs are divided on the sequence of amino-acids into three groups: Alpha, Beta and Gamma interferons. IFN-alpha has both anti-viral and immunomodulatory activities on target cells, and increases the awareness of infection or tumor cells by elevating antigen presentation to T lymphocytes. This protein has both anti-viral and immunomodulatory activities on target cells and involved both in ligand binding and signal transduction. Recombinant human IFNA7, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 20.7kDa (175aa) 18-28kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_066401

UniProt: P01567

Pathways: Signalistation JAK/STAT, Hepatitis C